Results 281 to 290 of about 633,913 (353)
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
FEBS Open Bio, EarlyView.PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
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Radiopacity of impression materials
Oral Surgery, Oral Medicine, Oral Pathology, 1979The radiographic densitites of twenty-six impression materials were measured and the values expressed as an equivalent thickness of aluminum. Under simulated clinical conditions, only ten of the materials tested could be consistently distinguished from the bone structure in periapical radiographs. It was far more dificult to detect objects with beveled
Bruce Haasken +2 more
openaire +3 more sources
Impression Materials and Virus
The Journal of the American Dental Association, 1991Results of this study indicate that impression materials vary in their ability to absorb and retain virus. Disinfection procedures specific for each material or groups of materials should be developed.
Donald E. Gerhardt, Robert J. Sydiskis
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Cytotoxicity of impression materials
The Journal of Prosthetic Dentistry, 1993The purpose of this study was to assess the potential cytotoxicity of impression materials. The impression material brands tested included Impregum, Reprosil, Surgident, Permlastic, Jeltrate Regular and Jeltrate Fast Set. These impression materials and their components were tested for their possible cytotoxic effects by three different methods.
Donald E. Gerhardt, Robert J. Sydiskis
openaire +3 more sources