Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Distinguishing the importance of different charge trapping centers in CaF2-based 2D material MOSFETs [PDF]
Crystalline CaF2 is drawing huge attentions due to its great potential of being the gate dielectric of two-dimensional (2D) material MOSFETs. It is deemed to be much superior than boron nitride and traditional SiO2 because of its larger dielectric constant, wider band gap, and lower defect density.
arxiv
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti+3 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
Advances in alginate impression materials: a review [PDF]
Alginate is an elastic irreversible hydrocolloid which has various applications in dentistry. The applications of alginates include making impressions of edentulous and partially edentulous arches, duplication of casts, and for making study models ...
Alaghari, Sahithi+3 more
core +2 more sources
Linear dimensional changes in plaster die models using different elastomeric materials
Dental impression is an important step in the preparation of prostheses since it provides the reproduction of anatomic and surface details of teeth and adjacent structures. The objective of this study was to evaluate the linear dimensional alterations in
Jefferson Ricardo Pereira+4 more
doaj +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Image Domain Dual Material Decomposition for Dual-Energy CT using Butterfly Network [PDF]
Dual-energy CT (DECT) has been increasingly used in imaging applications because of its capability for material differentiation. However, material decomposition suffers from magnified noise from two CT images of independent scans, leading to severe degradation of image quality. Existing algorithms achieve suboptimal decomposition performance since they
arxiv +1 more source
Порівняльне дослідження плинності еластичних матеріалів для функціональних відбитків у хворих з повною адентією [PDF]
COMPARATIVE STUDY OF FLOW OF ELASTIC MATERIALS FOR FINAL IMPRESSIONS IN EDENTULOUS PATIENTS ABSTRACT The aim of the present study was a comparative study of flow of elastic masses of the 3rd type of viscosity according to ISO, polyester and ...
Глазунов, А.О.+1 more
core
Background and aims. Several products have been marketed for disinfecting impression materials. The present study evaluated the effect of Deconex, Micro 10, Alprocid and Unisepta Plus sprays on Staphylococcus aureus and Candida albicans transferred to ...
Fereydoun Parnia +5 more
doaj