Results 121 to 130 of about 535,437 (301)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Use of Irreversible Hydrocolloid to Blockout Interproximal Spaces for an Easy Impression Taking

open access: yesFrontiers in Dentistry, 2009
Making impression to obtain an accurate working cast needs to use accurate impression materials such as polyether. On the other hand, polyether cannot be used easily in places with undercut such as excessive interproximal spaces and under the pontics of ...
A. Monzavi   +1 more
doaj  

Accuracy and Precision of Occlusal Contacts of Stereolithographic Casts Mounted by Digital Interocclusal Registrations [PDF]

open access: yes, 2016
Statement of problem Little peer-reviewed information is available regarding the accuracy and precision of the occlusal contact reproduction of digitally mounted stereolithographic casts.
Bansal, Naveen K.   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Systematic evaluation of perceived spatial quality [PDF]

open access: yes, 2003
The evaluation of perceived spatial quality calls for a method that is sensitive to changes in the constituent dimensions of that quality. In order to devise a method accounting for these changes, several processes have to be performed.
Berg, Jan, Rumsey, Francis
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

In Vitro Effect of Vent Size and Spacer Thickness on Pressure Produced during Maxillary Edentulous Impression Making by Different Impression Materials

open access: yesJournal of Islamic Dental Association of Iran, 2016
Background and Aim: Inappropriate transfer of pressure during final impression making in fabrication of complete denture can result in ridge resorption.
Tahereh Imani Fouladi   +5 more
doaj  

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