Results 191 to 200 of about 1,252,934 (262)

Chaos-enhanced manganese electrolysis: nodule suppression and improved efficiency using controllable chaotic electrical signals. [PDF]

Sci Rep
Yang J, Li C, Zhang Q, Wu Z, Zhang X, Liu P, Liu Z, Tao C, Zheng G, Yang Y, Wei H.   +10 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency. [PDF]

Nucleic Acids Res
Ochiai Y, Clifton BE, Le Coz M, Terenzio M, Laurino P.   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Publisher Correction: Photon shifting and trapping in perovskite solar cells for improved efficiency and stability. [PDF]

Light Sci Appl
Haque S, Alexandre M, Vicente AT, Li K, Schuster CS, Yang S, Águas H, Martins R, Ferreira RAS, Mendes MJ.   +9 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Improved efficiency using sequential automated immunoassays for syphilis screening in blood donors. [PDF]

J Clin Microbiol
Cheng A, Das A, Styles CE, Naing Z, Rawlinson WD, Gosbell IB.   +5 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Hybrid <i>Bis</i>-(Imidazole/Benzimidazole)-Pyridine Derivatives with Antifungal Activity of Potential Interest in Medicine and Agriculture via Improved Efficiency Methods. [PDF]

Pharmaceuticals (Basel)
Balaes T, Mangalagiu V, Antoci V, Amariucai-Mantu D, Diaconu D, Mangalagiu II.   +5 more
europepmc   +1 more source