Results 231 to 240 of about 9,646,676 (303)

From Anatomy to Innovation: Embedding Patient-Centered Design in Medical Education.

JMIR Med Educ
Koizia LJ, Vandekerckhove P, Howard S, Maisch B, Harris BHL.   +4 more
europepmc   +1 more source

The Impact of Comorbidities on Functional Outcomes After Rehabilitation in Stroke Patients. [PDF]

Healthcare (Basel)
Dimkić Tomić T, Djordjević O, Mitrović S, Dedijer Dujović S, Rosić S, Konstantinović L, Vidaković A.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Roles of beta synchronization for motor skill acquisition change after stroke. [PDF]

Brain Commun
Timmsen LS, Haverland B, Wolf S, Stagg CJ, Feldheim J, Luu TV, Schulz R, Schneider TR, Quandt F, Schwab BC.   +9 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Trichoscopic Evaluation of the Effectiveness of Topical Stemoxydine for Hair Restoration in Androgenetic Alopecia: A Prospective Pre-Post Single-Arm Exploratory Study. [PDF]

J Cosmet Dermatol
Elattar YA, Doghem NN, Amin MT, Hawwam SA.   +3 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Clinically Meaningful Improvement in Atopic Dermatitis According to Treatment Type in a Real- World Cohort. [PDF]

Acta Derm Venereol
Chew Bonilla E, Vega-Del Pilar YX, Vilchis Chaparro E, Lemini López A.   +3 more
europepmc   +1 more source