Results 261 to 270 of about 8,768,987 (313)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Product allocation and licensing of CIMMYT derived elite maize hybrids in sub-Saharan Africa [PDF]

, 2019
International Maize and Wheat Improvement Center
core  

Multimodal quality improvement project on reducing hospital perioperative thromboembolic events (Patient Safety Indicator-12). [PDF]

BMJ Open Qual
Peseski AM, Vail CJ, Kuchibhatla M, Hauser J, Bae J, Shannon RP, Sangvai D, Ortel TL, Wahidi MM.   +8 more
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Assessing therapeutic decisions in generalized myasthenia gravis: Study protocol. [PDF]

PLoS One
Gutiérrez-Gutiérrez G, Gómez-Ballesteros R, Sotoca J, Ares A, Villaverde R, Reyes V, Armangué T, Salas E, Díaz-Abós P, Rebollo P, Sarmiento M, Escobar I, Maurino J, Querol L.   +13 more
europepmc   +1 more source

Safety and Efficacy of a "High and Low Molecular Weight Hyaluronic Acid Hybrid Complex" Injection for Face Rejuvenation. [PDF]

J Cosmet Dermatol
Yazdanparast T, Ayatollahi A, Samadi A, Sabzvari A, Kafi H, Firooz A.   +5 more
europepmc   +1 more source

Uncovering the breeding contribution of transposable elements from landraces to improved varieties through pan-genome-wide analysis in rice. [PDF]

Front Plant Sci
Li X, Dai X, He H, Chen W, Qian Q, Shang L, Guo L, He W.   +7 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Quality improvement initiative to improve safe injection practices by nurses in labour room of a tertiary care centre, India. [PDF]

BMJ Open Qual
Pradeep J, Kumari P, Puri M, Pradeep C, Gauba A.   +4 more
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source