Results 141 to 150 of about 1,327,800 (294)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A study of external intervention and school improvement in schools facing challenging circumstances [PDF]
Central Government has identified a group of schools deemed to be 'Schools facing Challenging Circumstances'. These schools tend to be low attaining schools that serve socio-economically deprived communities.
Chapman, Christopher James
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ACHIEVING SUCCESSFUL IMPLEMENTATION OF IMPROVEMENT PROJECTS IN ELDERLY CARE ORGANIZATIONS IMPLEMENTATION OF BREAKTHROUGH PROJECTS IN SPECIAL ACCOMMODATIONS FOR ELDERLY [PDF]
, 2005 Recent innovations in the medical field improve the opportunities to treat diseases and injuries better, even at an advanced age. In addition, the Swedish population is reported as growing steadily older. In order to cope with those challenges, Swedish
Kostak, Esra, Lobaiko, Viktoria
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The science of improvement in teacher preparation
, 2016 Due to new United States (U.S.) Federal Regulations and the Council for the Accreditation of Educator Preparation standards focusing on K-12 student outcomes, teacher education providers are facing the challenge of gaining access to data on their ...
Weeldreyer, Laura +2 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Science Production in Iran: The Scenario of Iranian Medical Journals [PDF]
, 2009 In Iran, the number of published articles has increased significantly in the basic and applied sciences including medicine and its subspecialties during the recent years.
Farzaneh Aminpour +3 more
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Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source