Results 101 to 110 of about 1,338,886 (313)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Improvement on preoperative enema method for patients with low-set rectal cancer of fungating type
[目的 ]了解菜花型低位直肠癌灌肠方法改进后的效果。 [方法 ]以甲硝唑加开塞露灌肠 ,改变卧位、灌肠液温度、插管方法、肛管等 ,并与传统清洁灌肠方法对照比较肠道清洁程度、术后肛门排气恢复时间及术后并发症情况。 [结果 ]实验组术后肛门排气恢复时间较对照组短 ,术后并发症较对照组少。 [结论 ]该方法简便有效 ,副反应少 ,是一种切实可行的方法。
吴霞, 陈观华, 陈红湛
doaj
Objective: Indigenous herbs alone or in combination are widely used in Indian system of medicine to treat innumerable ailments since time immemorial.
Prafulla Kumar Sahu +4 more
core +1 more source
Large neighborhood local search for the maximum set packing problem [PDF]
In this paper we consider the classical maximum set packing problem where set cardinality is upper bounded by a constant k. We show how to design a variant of a polynomial-time local search algorithm with performance guarantee (k + 2)/3.
Sviridenko, Maxim +3 more
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Background Student evaluations of teaching (SET) are widely used in medical education as a tool to improve teaching quality. However, biases in SET can undermine their effectiveness.
Yuanheng Li +14 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
An oral microbiome model for predicting atherosclerotic cardiovascular disease
ObjectiveThis study aimed to construct a predictive model for the early onset of atherosclerotic cardiovascular disease (ASCVD) by integrating oral microbiome data with traditional clinical risk factors.MethodsA retrospective study was conducted ...
Qiuli Sui, Jie Yu, Shuping Cui
doaj +1 more source
Upsetting the Foundations for Mathematics
Starting with a review of the kinds of questions a foundation for mathematics should address, this paper provides a critique of set theoretical foundations, a proposal that multiple interconnected categorical foundations would be an improvement, and a ...
Lawrence Neff Stout
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

