Results 171 to 180 of about 3,983,216 (298)

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

High‐Current‐Density Acidic CO2 Electroreduction to Formic Acid Enabled by Multiscale Microenvironment Regulation Over Defect‐Rich Sn/SnOx

Advanced Science, EarlyView.
Acidic CO2 electroreduction to formic acid is enabled by integrating mixed Sn/SnOx nanoclusters, K+‐regulated interfacial solvation, and Janus wettability. Coordinated control of active sites, interfacial water, and gas‐liquid transport suppresses hydrogen evolution and delivers approximately 85% HCOOH Faradaic efficiency at 400 mA cm−2.
Qiaoqi Guo, Bowen Jiang, Le Huang, Kunyu Jiang, Rongrong Tang, Qinong Zhu, Huajun Feng, Mengyang Fan, Yijing Xia   +8 more
wiley   +1 more source

Design of a Novel Diamine Biosensor to Guide the Engineering of Escherichia coli for Cadaverine Overproduction

Advanced Science, EarlyView.
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng, Getao Liu, Ding Ma, Jiaxiang Yuan, Xinyi Zhang, Weihao Wang, Chen Ma, Yang Liao, Siyuan Gao, Lei Qin, Jiao Feng, Sheng Xu, Xin Wang, Kequan Chen   +13 more
wiley   +1 more source

Breeding innovations focused on drought tolerance, and Nitrogen and phosphorus uptake, for sustainable and climate-resilient sugarcane. [PDF]

Front Plant Sci
Perera MF, Racedo J, Sá ACS, Vomero JVM, Almeida Balsalobre TW, Soares MR, Carneiro MS.   +6 more
europepmc   +1 more source

Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt

Advanced Science, EarlyView.
A natural microbial consortium employing a cross‐feeding strategy forms a stratified biofilm that promotes endophytic colonization of auxotrophic Flavobacterium. This enhanced colonization activates plant systemic resistance, effectively suppressing Fusarium wilt.
Xianfeng Ye, Changsheng Xu, Shuai Yao, Jiming Shen, Zeyuan Li, Yu Zhang, Fan Wu, Xinjie Li, Yanling Ji, Lei Zhang, Yan Huang, Zhoukun Li, Huayu Qin, Zhongli Cui   +13 more
wiley   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Integrated Algal Bioenergy Platforms: Advances in Microbial Fuel Cell Integration and Nanotechnology-Enabled Biorefineries. [PDF]

Nanomaterials (Basel)
Mohamed YS, Steele S, Khafaga DSR, Basem Y, Shawky AM, Mostafa YG, Solyman SM.   +6 more
europepmc   +1 more source

Grain‐Boundary‐Enriched Cocatalyst Coupled With CuSCN Hole Transport Layer for Efficient Solar Water Oxidation in BiVO4 Photoanode

Advanced Science, EarlyView.
A grain‐boundary‐enriched NiFe cocatalyst is coupled with a CuSCN hole transport layer on BiVO4 photoanodes. The integrated architecture promotes hole extraction, interfacial charge transfer, and surface OER kinetics, highlighting cocatalyst microstructure regulation as a complementary strategy to hole transport layer engineering. ABSTRACT Solar‐driven
Wei Zhao, Yaorong He, Xiao Wang, Lin Zhu, Tong Su, Yujie Zhou, Xiang Li, Peiyao Du, Xiaoquan Lu   +8 more
wiley   +1 more source

Factors Associated With Research Productivity Among Canadian Plastic Surgery Residents. [PDF]

Plast Surg (Oakv)
Guyn C, Lee J, Budden C.
europepmc   +1 more source

Productivity improvement [PDF]

, 2007
openaire   +1 more source