Switching Spike Plasticity Shapes ACE2 Engagement Across SARS‐CoV‐2 Variants
Conformational plasticity governs SARS‐CoV‐2 spike function and ACE2 recognition. Using high‐speed AFM and single‐molecule force spectroscopy, we analyzed the ancestral spike and nine variants, revealing progressive rigidification from Delta, variable plasticity in Omicron sublineages, and JN.1 compaction.
Sarah Stainer +17 more
wiley +1 more source
The Necessity and Feasibility of Implementing Regenerative Practices in Pasture-Based Beef Cattle Farming. [PDF]
Szabó F, Holló G.
europepmc +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
Deciphering Stress Resilience in Black Pepper (<i>Piper nigrum</i> L.): From Current Advances to Emerging Opportunities. [PDF]
Cheng A, Ee KP.
europepmc +1 more source
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia +10 more
wiley +1 more source
Research on the allocation efficiency of integrated medical and older adult care institutions using the Malmquist productivity index. [PDF]
Wang L, Kong X, Zhu H, Liu H, Yu X.
europepmc +1 more source
Dual Nickel/Photoredox‐Catalyzed Regio‐ and Enantioselective Alkenylation of Epoxides
Ni/photoredox‐catalyzed stereoconvergent cross‐electrophile coupling of racemic epoxides with alkenyl bromides is described, affording β‐alkenyl products with up to 95% ee, excellent E‐selectivity, and complete regiocontrol. These versatile intermediates enable diverse chiral synthons; mechanistic studies suggest a halide ring‐opening followed by ...
Hongyan Lan +4 more
wiley +1 more source
Non-Thermal Plasma-Mediated Redox Signaling and Microbiome Interactions for Abiotic Stress Adaptation: Molecular Insights and Future Prospects for Sustainable Agriculture. [PDF]
Javed R, Ji G, Sun Q, Huang F.
europepmc +1 more source
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta +6 more
wiley +1 more source
Biology-aware scaling of microalgal biofuels: bioprocess constraints and data-centric digital twins. [PDF]
Correa-Aguado HC +8 more
europepmc +1 more source

