Results 81 to 90 of about 1,483,275 (274)
Lightning Impulse Ageing of HV Cable Insulation
, 2009 Lightning impulses can lead to accelerated ageing of extruded cables. Electrical behaviour of a dielectric material when experiencing a lightning impulse is different to that for DC or power frequency applied voltages.
Dao, N L, Swingler, S G, Lewin, P L
core +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Mokslas: Lietuvos Ateitis, 2012 The article describes the possibility of generating a micro and sub-microsecond magnetic impulse reaching 1–10 T, investigates various configurations of microcoils and discusses the principal circuit of a magnetic field impulse generator of microsecond ...
Audrius Grainys
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Impulse ageing of polymeric materials
, 2011 Impulse over-voltage is a common phenomenon in electric power systems. A switching impulse is created by a switching surge or local fault while a lightning impulse is due to direct lightning strike to high voltage plant such as an overhead line.
Dao, Ngoc Long
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Practical simulation and modelling of lightning impulse voltage generator using marx circuit [PDF]
, 2014 Standard impulse waveform have similar characteristics as that of lightning strike and can be used for testing the strength of electrical equipment. For producing high voltage pulses Marx generator is the most popular and is most widely used method ...
Verma, Vivek Kumar
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
A General Class of Impulsive Evolution Equations
Topological Methods in Nonlinear Analysis, 2015 One of the novelty of this paper is the study of a general class of impulsive differential equations, which is more reasonable to show dynamics of evolution processes in Pharmacotherapy. This fact reduces many difficulties in applying analysis methods and techniques in Bielecki's normed Banach spaces and thus makes the study of existence and uniqueness
Fečkan, Michal, Wang, JinRong
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source