Results 51 to 60 of about 6,983 (265)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

新型脉动发生机构研究及运动仿真

open access: yesJixie chuandong, 2006
Structural characteristics and kinematics feature of a new impulse generator are analyzed. The relations of theoretical outline of cam, swing angle of rocker and dimension of link are established.
杨刚   +4 more
doaj  

Grid connection method of gravity energy storage generator motor based on voltage index sensitivity analysis

open access: yesEnergy Informatics
The basic requirements for the grid connection of the generator motor of the gravity energy storage system are: the phase sequence, frequency, amplitude, and phase of the voltage at the generator end and the grid end must be consistent.
Qingshan Wang   +3 more
doaj   +1 more source

Nd-Fe-B permanent magnet generator and voltage stabilizing control technology for vehicles

open access: yesAdvances in Mechanical Engineering, 2016
In this study, the tangential magnetic field Nd-Fe-B permanent magnet generator is designed and analyzed. In the generator, the adjacent permanent steel is sequentially arranged on the radial groove by the way of same polarity-oriented manner.
Xueyi Zhang   +6 more
doaj   +1 more source

Improving the performance of LOX/kerosene upper stage rocket engines

open access: yesPropulsion and Power Research, 2017
Improved liquid rocket engine cycles were proposed and analyzed via comparison with existing staged combustion and gas-generator cycles. The key features of the proposed cycles are regenerative cooling of thrust chamber by oxygen and subsequent use of ...
IgorN. Nikischenko   +2 more
doaj   +1 more source

Acoustic Sounding of Hydraulic Fractures in a Low-Permeability Reservoir

open access: yesMathematics, 2022
Theoretical models indicate the possibility of diagnosing the presence and the conductivity of the hydraulic fractures in reservoirs of the permeability of order milli Darcy by means of an acoustic TV set, which is a cylindrical probe of the length of ...
Vladislav Sh. Shagapov   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Employment of mud-pulse generator for improvement of efficiency of a wellbore producing in complex mining and geological conditions

open access: yesPetroleum Research
In this study, the employment of mud-pulse generators to improve the efficiency of wellbores under complex mining and geological conditions is examined. A systemic analysis is made of the primary theoretical basis of the study.
Bibinur Akhymbayeva
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

A General Class of Impulsive Evolution Equations

open access: yesTopological Methods in Nonlinear Analysis, 2015
One of the novelty of this paper is the study of a general class of impulsive differential equations, which is more reasonable to show dynamics of evolution processes in Pharmacotherapy. This fact reduces many difficulties in applying analysis methods and techniques in Bielecki's normed Banach spaces and thus makes the study of existence and uniqueness
Fečkan, Michal, Wang, JinRong
openaire   +3 more sources

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