Results 41 to 50 of about 529,826 (242)

Evaluation of the cavitation generator efficiency in the hydro impulsive loosening of a coal-bed [PDF]

open access: yesE3S Web of Conferences, 2019
The paper presents the results of mining and experimental work, bench tests and theoretical studies of the energy characteristics of the stationary and pulsating fluid flow, which allow to estimate the efficiency of the cavitation generator in the hydro ...
Zberovskyi Vasyl   +2 more
doaj   +1 more source

An Accurate Evaluation of Switching Impulse Voltages for High-Voltage Tests

open access: yesEnergies, 2022
For assessment of the insulation performance of high-voltage (HV) equipment installed in extra-high-voltage (EHV) systems, switching impulse voltage tests are performed in an HV testing laboratory.
Peerawut Yutthagowith
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Lightning Impulse Ageing of HV Cable Insulation

open access: yes, 2009
Lightning impulses can lead to accelerated ageing of extruded cables. Electrical behaviour of a dielectric material when experiencing a lightning impulse is different to that for DC or power frequency applied voltages.
Dao, N L, Swingler, S G, Lewin, P L
core   +1 more source

IR-UWB antenna with built-in impulse-like waveform generator for impulse radar applications

open access: yesAIP Advances
This paper presents a novel impulse-radio ultra-wideband (IR-UWB) pulsed radar antenna integrated with an impulse generator circuit, designed and investigated for IR-UWB radar imaging applications.
D. Lee
doaj   +1 more source

Acoustic Sounding of Hydraulic Fractures in a Low-Permeability Reservoir

open access: yesMathematics, 2022
Theoretical models indicate the possibility of diagnosing the presence and the conductivity of the hydraulic fractures in reservoirs of the permeability of order milli Darcy by means of an acoustic TV set, which is a cylindrical probe of the length of ...
Vladislav Sh. Shagapov   +2 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

新型脉动发生机构研究及运动仿真

open access: yesJixie chuandong, 2006
Structural characteristics and kinematics feature of a new impulse generator are analyzed. The relations of theoretical outline of cam, swing angle of rocker and dimension of link are established.
杨刚   +4 more
doaj  

Grid connection method of gravity energy storage generator motor based on voltage index sensitivity analysis

open access: yesEnergy Informatics
The basic requirements for the grid connection of the generator motor of the gravity energy storage system are: the phase sequence, frequency, amplitude, and phase of the voltage at the generator end and the grid end must be consistent.
Qingshan Wang   +3 more
doaj   +1 more source

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