Results 71 to 80 of about 7,058 (264)

Effective Simulation Approach for Lightning Impulse Voltage Tests of Reactor and Transformer Windings

open access: yesEnergies, 2020
In this paper, an effective simulation method for lightning impulse voltage tests of reactor and transformer windings is presented. The method is started from the determination of the realized equivalent circuit of the considered winding in the wide ...
Piyapon Tuethong   +2 more
doaj   +1 more source

Impulsive control of a nuclear spin generator

open access: yesJournal of Computational and Applied Mathematics, 2003
Impulsive control of a nuclear spin generator is considered. Let be \[ X^T= (X_1,X_2,X_3),\qquad A= \begin{pmatrix} -\beta & 1 & 0\\ -1 &\beta(\gamma- 1) & 0\\ 0 & 0 & -\alpha\beta\end{pmatrix}, \] \[ \Phi(X)= \beta\gamma\begin{pmatrix} 0\\ -X_2 X_3\\ X^2_2\end{pmatrix},\qquad \alpha\in (0,1],\quad \beta,\gamma\in \mathbb{R}_+. \] The impulsive control
Sun, Jitao, Zhang, Yinping
openaire   +2 more sources

Periodic Solutions Generated by Impulses for State-Dependent Impulsive Differential Equation [PDF]

open access: yesDiscrete Dynamics in Nature and Society, 2015
We study the existence of periodic solutions for a class of state-dependent impulsive differential systems via geometrical analysis methods. Our results show that these periodic solutions are generated by impulses. Moreover, numerical simulations are used to examine the existence of the periodic solutions.
Qizhen Xiao, Binxiang Dai
openaire   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

High magnetic field generator of sub-microsecond duration / Mikrosekundinės trukmės magnetinių impulsų generatorius

open access: yesMokslas: Lietuvos Ateitis, 2012
The article describes the possibility of generating a micro and sub-microsecond magnetic impulse reaching 1–10 T, investigates various configurations of microcoils and discusses the principal circuit of a magnetic field impulse generator of microsecond ...
Audrius Grainys
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

A General Class of Impulsive Evolution Equations

open access: yesTopological Methods in Nonlinear Analysis, 2015
One of the novelty of this paper is the study of a general class of impulsive differential equations, which is more reasonable to show dynamics of evolution processes in Pharmacotherapy. This fact reduces many difficulties in applying analysis methods and techniques in Bielecki's normed Banach spaces and thus makes the study of existence and uniqueness
Fečkan, Michal, Wang, JinRong
openaire   +3 more sources

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