Results 61 to 70 of about 7,055 (265)

Impulsive control of a nuclear spin generator

open access: yesJournal of Computational and Applied Mathematics, 2003
Impulsive control of a nuclear spin generator is considered. Let be \[ X^T= (X_1,X_2,X_3),\qquad A= \begin{pmatrix} -\beta & 1 & 0\\ -1 &\beta(\gamma- 1) & 0\\ 0 & 0 & -\alpha\beta\end{pmatrix}, \] \[ \Phi(X)= \beta\gamma\begin{pmatrix} 0\\ -X_2 X_3\\ X^2_2\end{pmatrix},\qquad \alpha\in (0,1],\quad \beta,\gamma\in \mathbb{R}_+. \] The impulsive control
Sun, Jitao, Zhang, Yinping
openaire   +2 more sources

Periodic Solutions Generated by Impulses for State-Dependent Impulsive Differential Equation [PDF]

open access: yesDiscrete Dynamics in Nature and Society, 2015
We study the existence of periodic solutions for a class of state-dependent impulsive differential systems via geometrical analysis methods. Our results show that these periodic solutions are generated by impulses. Moreover, numerical simulations are used to examine the existence of the periodic solutions.
Qizhen Xiao, Binxiang Dai
openaire   +3 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

High magnetic field generator of sub-microsecond duration / Mikrosekundinės trukmės magnetinių impulsų generatorius

open access: yesMokslas: Lietuvos Ateitis, 2012
The article describes the possibility of generating a micro and sub-microsecond magnetic impulse reaching 1–10 T, investigates various configurations of microcoils and discusses the principal circuit of a magnetic field impulse generator of microsecond ...
Audrius Grainys
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang   +13 more
wiley   +1 more source

A General Class of Impulsive Evolution Equations

open access: yesTopological Methods in Nonlinear Analysis, 2015
One of the novelty of this paper is the study of a general class of impulsive differential equations, which is more reasonable to show dynamics of evolution processes in Pharmacotherapy. This fact reduces many difficulties in applying analysis methods and techniques in Bielecki's normed Banach spaces and thus makes the study of existence and uniqueness
Fečkan, Michal, Wang, JinRong
openaire   +3 more sources

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