Results 31 to 40 of about 529,826 (242)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impulse TDR and its Application to Characterisation of Antennas [PDF]

open access: yes, 2011
Passive microwave systems are traditionally characterised in the frequency-domain with a vector network analyser (VNA). The measurement of antennas typically takes place in an anechoic chamber where the interference from spurious reflections and outside ...
McCabe, Steven Owen
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Impulse TDR and its application to measurement of antennas [PDF]

open access: yes, 2011
The traditional stimulus signal used in a time-domain reflectometer (TDR) is a voltage step. We propose an alternative technique, whereby an impulse generator is employed in place of the step generator in a TDR.
Scott, Jonathan B., McCabe, Steven Owen
core  

Analysis and prediction of the stability of train control systems to ultra-wideband electromagnetic pulses of intentional action

open access: yesВестник Научно-исследовательского института железнодорожного транспорта, 2020
Problem of ensuring stability of railway automation systems to ultra-wideband pulses of an electromagnetic field is considered. These pulses can be used to intentionally affect the equipment of these systems.
D. V. Komnatnyy
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The forming and emission of high power electromagnetic pulses

open access: yesITM Web of Conferences, 2018
An impulse energy source, a power conditioning system and an electromagnetic field emitter are essential to generate an electromagnetic field pulse (EMFP) with a specific frequency bandwidth.
Jakubiuk Kazimierz   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

TRANSMISSION AND RECEPTION OF UWB SIGNALS BASED ON ANTENNA DECODING

open access: yesInformation and Telecommunication Sciences, 2018
Background. A new idea for receiving and transmitting impulse radio ultrawideband signals with Pulse Position Coding (PPC) in transmitter station and antenna decoding in receiver station is proposed.
Gleb Avdeyenko   +2 more
doaj   +1 more source

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