Exhaled nitric oxide during infancy as a risk factor for asthma and airway hyperreactivity [PDF]
Childhood asthma is often characterised by elevated exhaled nitric oxide (eNO), decreased lung function, increased airway reactivity and atopy; however, our understanding of when these phenotypic airway characteristics develop remains unclear. This study
Chang, Daniel +7 more
core +1 more source
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig +4 more
wiley +1 more source
Cluster Analysis to Identify Distinct Asthma Phenotypes in the ATLANTIS Cohort
This study identified four clinically distinct asthma clusters. The most severe cluster was characterized by type 2 inflammation and exhibited both large and small airways obstruction, as well as air trapping on CT. Patients in the earlier‐onset cluster exhibited more severe bronchial hyperresponsiveness despite a relatively preserved lung function ...
Pauline J. M. Kuks +18 more
wiley +1 more source
Can Oscillometry Replace Spirometry as a Major Tool for Lung Function Testing? – An Overview
Developing countries face a huge challenge in managing obstructive lung disorders due to frequency, severity, management, and economic impact. Spirometry has been the popular choice to assess the severity and reversibility of airflow obstruction, but the
Jaymohan Unnithan +3 more
doaj +1 more source
Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]
Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz +51 more
core +14 more sources
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 264-266, March 2025.
Kirsten E. Stewart +3 more
wiley +1 more source
ABSTRACT Background Childhood acute lymphoblastic leukemia (ALL) survivors face an increased risk of pulmonary function deficit (PFD), which may affect physical functioning. We aimed to evaluate parent proxy‐ and self‐reported physical functioning and the association with PFD and abnormal bronchodilator response ( + BDR) among survivors versus controls.
Sonja Izquierdo Riis Meyer +9 more
wiley +1 more source
Feasibility of omega-3 fatty acid supplementation as an adjunct therapy for people with chronic obstructive pulmonary disease: study protocol for a randomized controlled trial [PDF]
There is evidence to support the use of supplementation with long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) from oily fish or fish oil for the treatment of various inflammatory diseases such as rheumatoid arthritis.
Coates, Alison M +7 more
core +3 more sources
ABSTRACT Background Pulmonary complications are a major cause of morbidity and mortality in pediatric and young adult hematopoietic stem cell transplant (HSCT) recipients. The impact of preexisting lung dysfunction on posttransplant outcomes remains understudied. Methods In a multi‐institutional prospective cohort of 444 patients (≤24 years) undergoing
Jane Koo +40 more
wiley +1 more source
Background There is increasing evidence of small airway abnormalities in smokers despite normal spirometry. The concavity in the descending limb of the maximum expiratory flow curve (MEFV) is a recognised feature of obstruction and can provide ...
Hooria Alowiwi +6 more
doaj +1 more source

