Results 61 to 70 of about 984,438 (297)
High‐altitude tunnel‐catenary gap impulse discharge characteristics and breakdown voltage correction
High Voltage, 2023 Air gap impulse discharge characteristics of railway tunnel‐catenary at high‐altitude are of great significance to the electrical insulation design. The existing altitude correction methods for non‐uniform air gaps are not applicable to tunnel‐catenary ...
Yi Liao +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
High Voltage, 2022 The roof arrester of electric multiple units (EMU) can efficiently limit the overvoltage, and ensure the safe operation of the EMU electrical equipment.
Qizhe Zhang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Lightning Impulse Ageing of HV Cable Insulation
, 2009 Lightning impulses can lead to accelerated ageing of extruded cables. Electrical behaviour of a dielectric material when experiencing a lightning impulse is different to that for DC or power frequency applied voltages.
Dao, N L, Swingler, S G, Lewin, P L
core +1 more source
Study on the optimisation of the end fittings of the DC disconnector
The Journal of Engineering, 2019 The disconnector is the key electrical equipment in DC field. In China, the ±1100 kV DC project uses the indoor DC field, where the switching impulse withstand voltage of the disconnector influences the clearance a lot.
Jindi Li +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
, 2011 Cross-linked polyethylene (XLPE) is commonly used within high voltage cable insulation. It has improved thermal and mechanical resistance compared to normal low density polyethylene (LDPE).
Dao, N L, Swingler, S G, Lewin, P L
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source