Results 51 to 60 of about 18,461 (262)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
HIGH VOLTAGE DIVIDER DNV-140I FOR INFORMATION-MEASURING SYSTEMS
Надежность и качество сложных систем, 2022 Background. The relevance of the use of high-voltage voltage dividers in information-measuring systems for monitoring and measuring impulse voltages is determined by the use of various electrical equipment and capable of withstanding exposure and ...
A.S. Ilin, I.A. Karchev, A.P. Voronov
doaj +1 more source
Breakdown process on rod–rod air gap under oscillating lightning impulse voltage
High Voltage, 2020 This study presents the discharge process on rod–rod electrodes under oscillating lightning impulse voltage. For this purpose, a measurement system has been developed to record the discharge currents at both rod electrodes simultaneously and to ...
Akif Gürlek
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Energies, 2020 This paper presents an effective technique based on an artificial neural network algorithm utilized for circuit parameter identification in lightning impulse generation for low inductance loads such as low voltage windings of a power transformer, a large
Piyapon Tuethong +3 more
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High‐altitude tunnel‐catenary gap impulse discharge characteristics and breakdown voltage correction
High Voltage, 2023 Air gap impulse discharge characteristics of railway tunnel‐catenary at high‐altitude are of great significance to the electrical insulation design. The existing altitude correction methods for non‐uniform air gaps are not applicable to tunnel‐catenary ...
Yi Liao +7 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
High Voltage, 2022 The roof arrester of electric multiple units (EMU) can efficiently limit the overvoltage, and ensure the safe operation of the EMU electrical equipment.
Qizhe Zhang +5 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Study on the optimisation of the end fittings of the DC disconnector
The Journal of Engineering, 2019 The disconnector is the key electrical equipment in DC field. In China, the ±1100 kV DC project uses the indoor DC field, where the switching impulse withstand voltage of the disconnector influences the clearance a lot.
Jindi Li +4 more
doaj +1 more source