Results 111 to 120 of about 91,295 (314)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Nonlinear AnalysisIn this paper, we deal with the relative controllability of linear and nonlinear damped fractional differential system with distributed delays and impulses.
Wangmin An, Danfeng Luo
doaj +1 more source
The effect of oxysterols on nerve impulses.
, 2018 International audienceThe propagation of nerve impulses in myelinated nerve fibers depends on a number of factors involving the myelin and neural axons.
Rym Ben Khalifa +30 more
core +1 more source
Razumikhin-type stability criteria for differential equations with delayed impulses [PDF]
, 2013 This paper studies stability problems of general impulsive differential equations where time delays occur in both differential and difference equations.
Quanxin Zhu +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Instantaneous impulses in multibody dynamics
, 2017 This paper considers instantaneous impulses in multibody dynamics. Instantaneous impulses may act on the multibody from its exterior or they may appear in its interior as a consequence of two of its parts interacting by an impact imposed by a unilateral ...
Lund University., Lidström, P.,
core +2 more sources
Existence of solutions to differential inclusions with fractional order and impulses
Electronic Journal of Differential Equations, 2010 We establish sufficient conditions for the existence of solutions for a class of initial value problem for impulsive fractional differential inclusions involving the Caputo fractional derivative.
Mouffak Benchohra +3 more
doaj
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source