Results 131 to 140 of about 313,820 (280)

ImputeBench: Benchmarking Single Imputation Methods

AbstractBiomedical data often contain missing values and in many applications missing value imputation (MVI) is an important part of the data analysis work-flow. However, the performance of MVI methods depends on details of the joint distribution of data and missingness patterns that are typically unknown in practice, making ana priorichoice of MVI ...
Robin Richter, Juliana F. Tavares, Anne Miloschewski, Monique M. B. Breteler, Sach Mukherjee   +4 more
openaire   +1 more source

Quantum Electrometry of Non‐Volatile Space Charges in Diamond

Advanced Optical Materials, EarlyView.
Charges are generated when nitrogen vacancy qubits in diamond are illuminated by light. Transport and trapping in an electric field leads to the formation of large, stable space charge patterns that dynamically screen applied electric fields, impacting electric field sensing and photoelectric detection.
Russell M Goldblatt, Nikolai Dontschuk, Daniel J McCloskey, Andy M Martin, Alexander A. Wood   +4 more
wiley   +1 more source

Benchmarking imputation methods for categorical biological data

Methods in Ecology and Evolution
Trait datasets are at the basis of a large share of ecology and evolutionary research, being used to infer ancestral morphologies, quantify species extinction risks, or evaluate the functional diversity of biological communities. These datasets, however,
Matthieu Gendre, Torsten Hauffe, Catalina Pimiento, Daniele Silvestro   +3 more
doaj   +1 more source

EVALUATING ALTERNATIVE METHODS OF DEALING WITH MISSING OBSERVATIONS - AN ECONOMIC APPLICATION [PDF]

This paper compares methods to remedy missing value problems in survey data. The commonly used methods to deal with this issue are to delete observations that have missing values (case-deletion), replace missing values with sample mean (mean imputation),
Onozaka, Yuko
core   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source

A genotype imputation method for de-identified haplotype reference information by using recurrent neural network

PLoS Computational Biology, 2020
Genotype imputation estimates the genotypes of unobserved variants using the genotype data of other observed variants based on a collection of haplotypes for thousands of individuals, which is known as a haplotype reference panel.
Kaname Kojima, Shu Tadaka, Fumiki Katsuoka, Gen Tamiya, Masayuki Yamamoto, Kengo Kinoshita, Ferhat Ay   +6 more
doaj  

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Conceptual framework as a guide to choose appropriate imputation method for missing values in a clinical structured dataset

BMC Medical Research Methodology
Background Missing data is a common challenge in structured datasets, and numerous methods are available for imputing these missing values. While all of these imputation methods address the issue of incomplete data, it is important to note that some ...
Marziyeh Afkanpour, Diyana Tehrany Dehkordy, Mehri Momeni, Hamed Tabesh   +3 more
doaj   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Applying multiple imputation on waterbird census data. Comparing two imputation methods. [PDF]

, 2014
Onkelinx, Thierry, Devos, Koen, Quataert, Paul   +2 more
openaire   +1 more source