Results 51 to 60 of about 318,466 (281)
PLoS ONE, 2020 BackgroundCommercial physical activity monitors have wide utility in the assessment of physical activity in research and clinical settings, however, the removal of devices results in missing data and has the potential to bias study conclusions.
R O'Driscoll +8 more
doaj +1 more source
Using linear predictors to impute allele frequencies from summary or pooled genotype data
, 2010 Recently-developed genotype imputation methods are a powerful tool for detecting untyped genetic variants that affect disease susceptibility in genetic association studies.
Stephens, Matthew, Wen, Xiaoquan
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Environment International, 2022 Urinary biomarkers are commonly used in epidemiological studies as surrogates or indicators of exposure to chemical substances. Evaluating the reliability of a biomarker is highly important because use of an unreliable marker may lead to ...
Yukiko Nishihama +3 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Transposable regularized covariance models with an application to missing data imputation [PDF]
, 2010 Missing data estimation is an important challenge with high-dimensional data arranged in the form of a matrix. Typically this data matrix is transposable, meaning that either the rows, columns or both can be treated as features.
Allen, Genevera I., Tibshirani, Robert
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
BMC Medical Research Methodology, 2019 Background Longitudinal categorical variables are sometimes restricted in terms of how individuals transition between categories over time. For example, with a time-dependent measure of smoking categorised as never-smoker, ex-smoker, and current-smoker ...
Anurika Priyanjali De Silva +4 more
doaj +1 more source
Fractional Imputation in Survey Sampling: A Comparative Review [PDF]
, 2015 Fractional imputation (FI) is a relatively new method of imputation for handling item nonresponse in survey sampling. In FI, several imputed values with their fractional weights are created for each missing item.
Kim, Jae Kwang +2 more
core +4 more sources
To Impute or not to Impute? A Review of Alternative Poverty Estimation Methods in the Context of Unavailable Consumption Data [PDF]
, 2018 There is an increasingly stronger demand for more frequent and accurate poverty estimates, despite the oftentimes unavailable household consumption data. We offer a review of alternative imputation methods that have been employed to provide poverty estimates in such contexts.
openaire +3 more sources