Results 131 to 140 of about 202,193 (268)
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Advanced Healthcare Materials, EarlyView.Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
Development and Current Practice in Using R at Statistics Austria [PDF]
Revista Română de Statistică, 2014 The popularity of R is increasing in national statistical offices not only for simulation tasks. Nowadays R is also used in the production process. A lot of new features for various tasks in official statistics have been developed over the last years and
Matthias Templ +2 more
doaj
Quantum Electrometry of Non‐Volatile Space Charges in Diamond
Advanced Optical Materials, EarlyView.Charges are generated when nitrogen vacancy qubits in diamond are illuminated by light. Transport and trapping in an electric field leads to the formation of large, stable space charge patterns that dynamically screen applied electric fields, impacting electric field sensing and photoelectric detection.
Russell M Goldblatt +4 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin +18 more
wiley +1 more source
Advanced Science, EarlyView.Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun +7 more
wiley +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
Advanced Science, EarlyView.This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells
Advanced Science, EarlyView.An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet +5 more
wiley +1 more source
BMC GenomicsBackground Integrating germplasm populations genotyped by different genotyping platforms via genotype imputation is a way to utilize accumulated genetic resources.
Huanhuan Zhao +6 more
doaj +1 more source
Statistical HLA type imputation from large and heterogeneous datasets
, 2012 An individual's Human Leukocyte Antigen (HLA) type is an essential immunogenetic parameter, influencing susceptibility to a variety of autoimmune and infectious diseases, to certain types of cancer and the likelihood of adverse drug reactions.I present and evaluate two models for the accurate statistical determination of HLA types for single-population
openaire +1 more source