Results 171 to 180 of about 1,318,109 (301)

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

A time-series dataset on sustainable development Goals compliance in Europe. [PDF]

Data Brief
Fernández-Macho J.
europepmc   +1 more source

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

Advanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan, Tao Luo, Yu Lin, Xiao‐Jun Wu, Wen‐Kang Shen, Jie Chen, Qian Lei, An‐Yuan Guo   +7 more
wiley   +1 more source

Evaluating Imputation-Based Fit Statistics in Structural Equation Modeling With Ordinal Data: The MI2S Approach

Suppanut Sriutaisuk, Yu Liu, Seungwon Chung, Hanjoe Kim, Фэй Гу   +4 more
openalex   +2 more sources

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Co-expression-wide association studies link genetically regulated interactions with complex traits. [PDF]

Nat Commun
Malakhov MM, Pan W.
europepmc   +1 more source

Artificial Intelligence Revolution in Transcriptomics: From Single Cells to Spatial Atlases

Advanced Science, EarlyView.
Single‐cell RNA sequencing and spatial transcriptomics have unveiled cellular heterogeneity and tissue organization with unprecedented resolution. Artificial intelligence (AI) now plays a pivotal role in interpreting these complex data. This review systematically surveys AI applications across the entire analytic workflow and offers practical guidance ...
Shixin Li, Tianxiang Xiao, Yuanyuan Lan, Chengxiao Wu, Zhouying Li, Rong Liu, Qing Fang, Chao Zhang   +7 more
wiley   +1 more source

The missing data problem in population genomics and statistical methods to address them. [PDF]

G3 (Bethesda)
Sethuraman A.
europepmc   +1 more source

Missing Growth, Imputation of Price Statistics and Channels of Creative Destruction

, 2019
Ville Markkanen
openalex   +1 more source

Reconstructing Coherent Functional Landscape From Multi‐Modal Multi‐Slice Spatial Transcriptomics by a Variational Spatial Gaussian Process

Advanced Science, EarlyView.
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang, Bowen Fu, Chuanchao Zhang, Xiaoping Liu   +3 more
wiley   +1 more source