Results 41 to 50 of about 199,171 (299)

Multiple imputation methods for bivariate outcomes in cluster randomised trials. [PDF]

open access: yes, 2016
Missing observations are common in cluster randomised trials. The problem is exacerbated when modelling bivariate outcomes jointly, as the proportion of complete cases is often considerably smaller than the proportion having either of the outcomes fully ...
DiazOrdaz, K   +3 more
core   +1 more source

A unifying framework for summary statistic imputation [PDF]

open access: yes, 2018
AbstractImputation has been widely utilized to aid and interpret the results of Genome-Wide Association Studies(GWAS). Imputation can increase the power to identify associations when the causal variant was not directly observed or typed in the GWAS. There are two broad classes of methods for imputation.
Wu, Yue   +2 more
openaire   +1 more source

Recovering High‐Quality Host Genomes from Gut Metagenomic Data through Genotype Imputation

open access: yesAdvanced Genetics, 2022
Metagenomic datasets of host‐associated microbial communities often contain host DNA that is usually discarded because the amount of data is too low for accurate host genetic analyses.
Sofia Marcos   +3 more
doaj   +1 more source

ImputeGAN: Generative Adversarial Network for Multivariate Time Series Imputation

open access: yesEntropy, 2023
Since missing values in multivariate time series data are inevitable, many researchers have come up with methods to deal with the missing data. These include case deletion methods, statistics-based imputation methods, and machine learning-based ...
Rui Qin, Yong Wang
doaj   +1 more source

Meta-imputation of transcriptome from genotypes across multiple datasets by leveraging publicly available summary-level data.

open access: yesPLoS Genetics, 2022
Transcriptome wide association studies (TWAS) can be used as a powerful method to identify and interpret the underlying biological mechanisms behind GWAS by mapping gene expression levels with phenotypes.
Andrew E Liu, Hyun Min Kang
doaj   +1 more source

Imputation and system modeling of acid-base state parameters for different groups of patients [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2022
The paper investigated the possibility of correct replacement of missing values in sets of acid-base state in the artery and vein in different groups of patients with different outcomes of the disease: “discharged”, “died”, “transferred to another ...
Dmitry I. Kurapeev   +3 more
doaj   +1 more source

Statistical Matching using Fractional Imputation

open access: yes, 2015
Statistical matching is a technique for integrating two or more data sets when information available for matching records for individual participants across data sets is incomplete. Statistical matching can be viewed as a missing data problem where a researcher wants to perform a joint analysis of variables that are never jointly observed.
Kim, Jae Kwang   +2 more
openaire   +3 more sources

Comparison of imputation and imputation-free methods for statistical analysis of mass spectrometry data with missing data

open access: yesBriefings in Bioinformatics, 2021
Abstract Missing values are common in high-throughput mass spectrometry data. Two strategies are available to address missing values: (i) eliminate or impute the missing values and apply statistical methods that require complete data and (ii) use statistical methods that specifically account for missing values without imputation ...
Sandra Taylor   +3 more
openaire   +4 more sources

Bayesian correction for covariate measurement error: a frequentist evaluation and comparison with regression calibration [PDF]

open access: yes, 2016
Bayesian approaches for handling covariate measurement error are well established, and yet arguably are still relatively little used by researchers. For some this is likely due to unfamiliarity or disagreement with the Bayesian inferential paradigm.
Bartlett, Jonathan W., Keogh, Ruth H.
core   +2 more sources

Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

open access: yesHGG Advances, 2022
Summary: Publicly available genome-wide association studies (GWAS) summary statistics exhibit uneven quality, which can impact the validity of follow-up analyses.
Florian Privé   +3 more
doaj   +1 more source

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