Results 101 to 110 of about 44,626 (291)

Integrated multi‐omics analysis of post‐translational modifications in head and neck squamous cell carcinoma: elucidating x‐ray and carbon ion irradiation effects

open access: yesPrecision Radiation Oncology, EarlyView.
This study underscores the critical role of PTMs in mediating cellular responses to X‐ray and Carbon ion irradiation radiotherapy in HNSCC. The integration of multi‐omics data provides insights into the molecular mechanisms underlying radiation‐induced changes, offering valuable clues for improving therapeutic outcomes and advancing precision medicine ...
Fan‐Tong Xia   +13 more
wiley   +1 more source

Knowledge‐based intensity‐modulated radiotherapy plans for cervical cancer with overlap volume of target and organs at risk

open access: yesPrecision Radiation Oncology, 2018
Objective To compare the differences in the dose‐volume histograms between knowledge‐based intensity‐modulated radiotherapy (K‐IMRT) plans and conventional IMRT (C‐IMRT) plans of 20 patients with cervical cancer.
Changdong Ma   +3 more
doaj   +1 more source

Implementation of IMRT in the radiotherapy department

open access: yesThe British Journal of Radiology, 2003
This paper describes the implementation of intensity modulated radiotherapy (IMRT) in a radiotherapy department. When preparing to set-up an IMRT programme, it is important to review departmental protocols with regard to immobilization, CT planning, treatment planning and verification.
H A, McNair   +4 more
openaire   +2 more sources

IMRT for Craniospinal Irradiation: A Dosimetric Comparison [PDF]

open access: yes, 2010
Purpose: This work tests the possibility of using IMRT to promote organ sparing for the treatment of CSI. The traditional CSI technique uses opposed lateral fields to treat the brain and posterior fields to treat the spine. Published manuscripts focusing
Harrison, A.   +11 more
core   +1 more source

The efficacy of concurrent chemoradiotherapy with or without nimotuzumab in high‐risk patients with locally advanced head and neck squamous cell carcinoma post‐surgery: A real‐world study

open access: yesPrecision Radiation Oncology, EarlyView.
Figure 1 Patient selection flowchart. CCRT, concurrent chemoradiotherapy; NCCRT, nimotuzumab and concurrent chemoradiotherapy. Abstract Purpose Patients with locally advanced head and neck squamous cell carcinoma (LA‐HNSCC) harboring high‐risk pathological features after radical surgery face high recurrence rates.
Yuejia Zhou   +8 more
wiley   +1 more source

Illusion of the target delineations in the large-target-volume IMRT (LV-IMRT) and the reduced-target-volume IMRT (RV-IMRT).

open access: yes, 2015
For the LV-IMRT group, the CTV at 70 Gy (CTV70, blue line) was delineated as the gross target volume (GTV, orange line) plus 7mm. The PTVs (cyan line) were constructed by expanding the CTVs by 7 mm.
Chia-Chun Chen (165881)   +3 more
core   +1 more source

Prognostic Value of MRI‐Derived Apparent Diffusion Coefficient in Intermediate‐Risk Prostate Cancer Treated With Definitive Radiotherapy

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Intermediate‐risk prostate cancer (IR‐PCa) is a heterogeneous disease with variable clinical outcomes despite established risk classification. We evaluated whether pretreatment tumor apparent diffusion coefficient (ADC) derived from multiparametric MRI was associated with long‐term outcomes and provided additional prognostic ...
Cem Onal   +4 more
wiley   +1 more source

Dosimetric Advantage of Combined IMRT for Whole Lung and Abdomen Irradiation for Wilms Tumor

open access: yesAdvances in Radiation Oncology
Purpose: In patients with Wilms tumor with lung metastases, a cardiac-sparing intensity modulated radiation therapy (CS-IMRT) technique is increasingly being adopted for whole lung irradiation.
Basil H. Chaballout, BA   +7 more
doaj   +1 more source

Timing for Radiotherapy Initiation After Dental Extraction and Risk of Osteoradionecrosis in Head and Neck Cancer Patients: A Systematic Review and Meta‐Analysis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) patients are advised to undergo dental extraction of teeth with poor prognosis prior to radiotherapy (RT) initiation to prevent osteoradionecrosis (ORN). However, insufficient healing time may result in persistent extraction wounds during RT, which constitute a potential risk factor for ORN, whereas ...
Nuo‐Zhou Liu   +4 more
wiley   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li   +12 more
wiley   +1 more source

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