Results 91 to 100 of about 264,997 (335)

C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution

open access: yesNature Communications, 2019
Single-cell transcriptomic profiling allows the exploration of cellular heterogeneity but commonly focuses on the 3′-end of the transcript. Here the authors introduce C1 CAGE, which detects the 5′ transcript end in a multiplexed microfluidic system.
Tsukasa Kouno   +25 more
doaj   +1 more source

Analisa Quality Of Service Layanan Video Call Berbasis Internet Protocol Multi Media Subsystem Pada Jaringan Ip Versi 6

open access: yesTechno, 2019
Tidak bisa dipungkiri perkembangan teknologi saat ini begitu pesat, khususnya perkembangan teknologi dibidang telekomunikasi. Sehingga semakin memberikan layanan kemudahan untuk melakukan aktivitas komunikasi.
Bongga Arifwidodo, Syahriful Ikhwan
doaj  

An IP Multimedia Subsystem Services Proxy Gateway Based on a JAVA Dynamic Module System

open access: yesApplied Sciences, 2018
By virtue of the rapid development of the Information and Communication Technology (ICT), people have owned various devices connected to the Internet to enjoy various emerging application services, such as multimedia related services.
Yi-Chun Chang, Jian-Wei Li, Jing-Hong Lv
doaj   +1 more source

Determination of incommensurate modulated structure in Bi2Sr1.6La0.4CuO6+{\delta} by aberration-corrected transmission electron microscopy

open access: yes, 2012
Incommensurate modulated structure (IMS) in Bi2Sr1.6La0.4CuO6+{\delta} (BSLCO) has been studied by aberration corrected transmission electron microscopy in combination with high-dimensional (HD) space description.
Binghui Ge   +49 more
core   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić   +4 more
wiley   +1 more source

Reduced Inspiratory Muscle Strength in Patients with Type 2 Diabetes Mellitus and Obstructive Sleep Apnoea

open access: yesJournal of Diabetes Research, 2017
Background. Obstructive sleep apnoea (OSA) is related to type 2 diabetes (T2DM), and it may be associated with reduced inspiratory muscle strength (IMS). The aim of this study was to investigate the IMS in patients with T2DM, with or without OSA. Methods.
Thomas Rehling   +4 more
doaj   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo   +22 more
wiley   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon   +13 more
wiley   +1 more source

A RARE PRESENTATION OF COARCTATION OF AORTA AS HEMORRHAGIC STROKE IN 22 YEARS OLD MALE: A CASE REPORT

open access: yesNational Journal of Medical Research, 2020
Spontaneous intracerebral hemorrhage in young adult is rare phenomena. most of them are due to rupture of arteriovenous malformation and cavernous angioma. Here we are reportinga rare presentation of aortic coarctation in adult as stroke.
Vivek Singh   +5 more
doaj  

Sequential inverse problems Bayesian principles and the\ud logistic map example [PDF]

open access: yes, 2010
Bayesian statistics provides a general framework for solving inverse problems, but is not without interpretation and implementation problems. This paper discusses difficulties arising from the fact that forward models are always in error to some extent ...
Duan, L., Farmer, C. L., Moroz, I. M.
core  

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