Advances in macromolecular crystallography at the Photon Factory: automation from crystallization to structural determination. [PDF]
The Structural Biology Research Center at the High Energy Accelerator Research Organization has developed advanced systems for macromolecular crystallography, including an automated crystallization screening system, a long‐wavelength crystallography beamline and an automated data‐collection system.The Structural Biology Research Center (SBRC) and the ...
Matsugaki N, Senda T.
europepmc +2 more sources
Mutational spectrum and genotype-phenotype correlation in Mexican patients with infantile-onset and late-onset Pompe disease. [PDF]
Mutational spectrum and genotype–phenotype correlation in a large case series of Pompe disease in Mexico with identification of two novel gene variants not reported previously. Abstract Background Pompe Disease (PD) is a metabolic myopathy caused by variants in the GAA gene, resulting in deficient enzymatic activity.
Martinez-Montoya V +25 more
europepmc +2 more sources
U.S. Citizen Children De Facto Deported to Mexico
Abstract Between 2000 and 2015, the U.S. deported unprecedented numbers of Mexican immigrants. During the same period, the population of U.S.‐born children living in Mexico doubled in size. This study estimates the number of U.S.‐born children who emigrated to Mexico from the United States in order to accompany a deported parent: de facto deported ...
Erin R. Hamilton +2 more
wiley +1 more source
Abstract Purpose Drug utilization research (DUR) contributes to inform policymaking and to strengthen health systems. The availability of data sources is the first step for conducting DUR. However, documents that systematize these data sources in Latin American (LatAm) countries are not known. We compiled the potential data sources for DUR in the LatAm
Luciane C. Lopes +39 more
wiley +1 more source
Scientific Output from Latin America and the Caribbean – Identification of the Main Institutions for Regional Open Access Integration Strategies [PDF]
Latin America is a region in which two thirds of the investment in research and development are funded by State resources. It can be foreseen that in the near future governments in the region will encourage and promote, or require by law or mandates ...
Babini, Dominique
core +1 more source
Leishmania mexicana: Novel Insights of Immune Modulation through Amastigote Exosomes
Exosomes are extracellular microvesicles of endosomal origin (multivesicular bodies, MVBs) constitutively released by eukaryotic cells by fusion of MVBs to the plasma membrane. The exosomes from Leishmania parasites contain an array of parasite molecules such as virulence factors and survival messengers, capable of modulating the host immune response ...
Laura Enedina Soto-Serna +10 more
wiley +1 more source
A Comprehensive Analysis on the Healthcare Systems in Latin America [PDF]
This comprehensive report summarizes and analyzes the current state of healthcare in Latin America, specifically in the countries of Mexico, Brazil, the Northern Triangle (El Salvador, Guatemala, and Honduras), the Andean Region (Ecuador, Peru, and ...
Calderon, Melinda +5 more
core +1 more source
Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production [PDF]
BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory debilitating disease that affects the joints in the early and productive phases of an individual’s life.
Ana L. Alemán-Navarro +12 more
core +1 more source
Abstract Book for the 27th Congress of the European Hematology Association
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley +1 more source
Background: Multiple myeloma (MM) is a genetically complex and heterogeneous disease with multiple genomic events associated with tumor development and progression.Chromosomal translocations into the immunoglobulin heavy‐chain (IgH) locus on 14q32 are the main primary events, occurring in about 50% of total MM cases.
X.‐H. Mao +25 more
wiley +1 more source

