Results 181 to 190 of about 26,813 (261)

Qingdainone, a novel bioactive compound in Realgar‒Indigo naturalis, induced apoptosis and differentiation in ATRA‐sensitive and ‐resistant acute promyelocytic leukaemia cells

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
1. Network pharmacology identified Qingdainone as a key bioactive compound in RIF. 2. Molecular docking revealed strong binding affinities of Qingdainone to targets such as CCND1, CDK1, CDK4, CASP3 and CASP7. 3. Qingdainone interfered proliferation and apoptosis, and promoted differentiation, of ATRA‐sensitive and ‐resistant APL cells, such that ...
Pengcheng Xu   +7 more
wiley   +1 more source

Characterizing the Bacterial Microbiome of the Invasive Vector <i>Aedes albopictus</i> in Hungary: A Pilot Study Using Oxford Nanopore Sequencing. [PDF]

open access: yesInt J Microbiol
Kurucz K   +8 more
europepmc   +1 more source

Facial Recognition Analyses Reveal Social Networks of Co‐Occurrence at Harbor Seal Haul‐Out Sites

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
By implementing the use of a non‐invasive, facial recognition software, SealNet 2.0, we have provided evidence of strong site fidelity and persistent networks of co‐occurring individuals in a wild harbor seal population. SealNet 2.0 provides an open‐source tool for the estimation of ecological measures such as site fidelity and connectivity, habitat ...
Wyatt Hall   +7 more
wiley   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

open access: yeseFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie   +5 more
wiley   +1 more source

Polygonati Rhizoma Attenuates Oxidative Stress‐Induced Senescence in Periodontal Ligament Stem Cells

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Network pharmacology identified the potential targets and pathways of Polygonati Rhizoma (PR) against aging‐related periodontitis through PPI, GO/KEGG enrichment, and molecular docking. Experimental validation in a D‐galactose‐induced senescence model of periodontal ligament stem cells showed that PR‐medicated serum attenuated cellular senescence and ...
Xinran Feng   +6 more
wiley   +1 more source

A Network-Based Association of IBD and Colorectal Cancer Using Proteomics Data. [PDF]

open access: yesProteomics Clin Appl
Dhami J   +8 more
europepmc   +1 more source

Curcumin in Food Technology: Trends, Challenges, and Innovative Perspectives Through Bibliometrics

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This graphical abstract summarizes the bibliometric trends, technological challenges, and innovative applications of curcumin in food technology, highlighting its relevance in functional foods, encapsulation systems, bioavailability enhancement, and industrial translation.
Vitória Damaceno Bueno   +1 more
wiley   +1 more source

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