Results 41 to 50 of about 2,861 (230)

Trait Negative Reputational Concerns Among In-group Members and In-group Favoritism in Minimal Groups

open access: yesLetters on Evolutionary Behavioral Science, 2022
People tend to behave more cooperatively with in-group members than out-group members, even in minimal group situations. This study investigated the relationship between trait reputational concern (fear of negative evaluation) from in-group members and in-group favoritism in minimal group contexts.
Takamasa Kajiwara   +2 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Subtle primes of in-group and out-group affiliation change votes in a large scale field experiment

open access: yesScientific Reports, 2022
Identifying the influence of social identity over how individuals evaluate and interact with others is difficult in observational settings, prompting scholars to utilize laboratory and field experiments.
Daniel Rubenson, Christopher T. Dawes
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Inter-group conflict and cooperation: field experiments before, during and after sectarian riots in Northern Ireland

open access: yesFrontiers in Psychology, 2015
The idea that cooperative groups out-compete less cooperative groups has been proposed as a theoretical possibility for the evolution of cooperation through cultural group selection.
Antonio S Silva, Ruth eMace
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Stigmatization of Overweight and Obese Peers among Children

open access: yesFrontiers in Psychology, 2017
Children get involved in social categorization. Thus, they are able to stigmatize peers as well as to show in-group favoritism theorized by Tajfel and Turner (1986). Moreover, according to Aboud's Cognitive-Developmental Theory (1988, 2003) the intensity
Roberta Di Pasquale, Laura Celsi
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy