Results 41 to 50 of about 549,445 (258)

院内大血管闭塞性卒中血管内治疗患者的临床特征及预后因素分析 Clinical Characteristics and Prognostic Analysis of Patients with Endovascular Treatment for In-Hospital Large Vessel Occlusive Stroke

Zhongguo cuzhong zazhi
目的 探讨院内发生的大血管闭塞性卒中行血管内治疗患者的临床特征、发病机制、血管内治疗及预后，为制订院内大血管闭塞性卒中预防策略提供参考信息。 方法 回顾性分析2020年7月—2023年7月因非缺血性卒中原因在徐州市中心医院住院期间发生大血管闭塞性卒中的45例患者（院内组）的临床资料。选择同期通过急诊绿色通道入院的大血管闭塞性卒中患者100例作为对照（院外组）。收集两组患者的基线资料、实验室指标以及血管内治疗相关资料，比较两组人口学信息、危险因素、发病机制及治疗结局 ...
张莉1，刘志广1，2，傅新民1，2，张洋2，宗海亮3 (ZHANG Li1, LIU Zhiguang1,2, FU Xinmin1,2, ZHANG Yang2, ZONG Hailiang3 )
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Stroke in a resource-constrained hospital in Madagascar [PDF]

BMC Research Notes, 2017
Stroke is reported as the most frequent cause of in-hospital death in Madagascar. However, no descriptive data on hospitalized stroke patients in the country have been published. In the present study, we sought to investigate the feasibility of collecting data on stroke patients in a resource-constrained hospital in Madagascar.
Stenumgård, Pål Sigurd, Rakotondranaivo, Miadana Joshua, Sletvold, Olav, Follestad, Turid, Ellekjær, Hanne   +4 more
openaire   +4 more sources

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Albumin-seeking near-infrared-II probe evaluating blood–brain barrier disruption in stroke

Journal of Nanobiotechnology
Background Blood-brain barrier (BBB) disruption after stroke is closely associated with brain tissue edema and neuronal injury, which requires accurate assessment. However, there is a lack of appropriate BBB imaging modality in vivo.
Hong-Jing Zhu, Ying-Ying Sun, Yijing Du, Sheng-Yu Zhou, Yang Qu, Shu-Yan Pang, Shoujun Zhu, Yi Yang, Zhen-Ni Guo   +8 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

What is new in the management of the acute ischaemic stroke?

Aktualności Neurologiczne, 2019
Stroke is a ma jor challenge for medicine in the 21st century. Despite modern diagnostics and even revolutionary methods of treatment, stroke is still the main cause of permanent disability and the second cause of death worldwide.
Piotr Sobolewski, Waldemar Brola, Aleksandra Wach-Klink, Tadeusz Frańczak-Prochowski, Karol Paciura, Grzegorz Kozera   +5 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

In-hospital mortality and its associated factors among hospitalized stroke patients at public hospitals of Eastern Ethiopia

BMC Cardiovascular Disorders
Background Stroke is rapidly developing clinical signs of focal/ global disturbance of cerebral function, with symptoms lasting more than 24 h and leading to death.
Ziyad Abas, Tigist Gashaw, Abera Jambo, Dumessa Edessa   +3 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source