Results 51 to 60 of about 605,476 (307)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

A Control Strategy of a Single-phase H6-type Grid-connected Inverter with Low Harmonic Current

open access: yesMATEC Web of Conferences, 2018
In order to reduce the total harmonic distortion (THD) of the grid-connected current caused by the high-frequency switching of the inverter, this paper combines the high efficiency single-phase H6-type inverter with LCL filter.
Chunxu Lin   +3 more
doaj   +1 more source

Research of double closed-loop control strategy for shunt active power filter

open access: yesGong-kuang zidonghua, 2013
The paper analyzed implementation principle of double closed-loop control strategy for shunt active power filter. In view of problems that PI control cannot track AC signal without static error and repetitive control has slow dynamic response speed, the ...
REN Zi-hui   +3 more
doaj   +1 more source

GPS Carrier Tracking Loop Performance in the presence of Ionospheric Scintillations [PDF]

open access: yes, 2005
The performance of several GPS carrier tracking loops is evaluated using wideband GPS data recorded during strong ionospheric scintillations. The aim of this study is to determine the loop structures and parameters that enable good phase tracking ...
Humphreys, Todd E.   +2 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Multi-Objective Optimal Tuning Framework of the Entire PMSM-Driven Servo System Considering High-Frequency Disturbance Suppression

open access: yesIEEE Access
A universal PMSM-driven servo system comprises cascaded PI controllers with a low-pass speed filter for high-frequency disturbance suppression. However, the speed filter and the current loop have received limited attention during the tuning of the speed ...
Zihan Tang   +4 more
doaj   +1 more source

Development of a Novel Tuning Approach of the Notch Filter of the Servo Feed Drive System

open access: yesJournal of Manufacturing and Materials Processing, 2020
To alleviate the vibration effect of the feed drive system, a traditional approach is to apply notch filters to suppress vibrations in the velocity loop.
Chung-Ching Liu   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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