Results 41 to 50 of about 1,063,217 (316)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Assessing database and network threats in traditional and cloud computing [PDF]

open access: yes, 2013
Cloud Computing is currently one of the most widely-spoken terms in IT. While it offers a range of technological and financial benefits, its wide acceptance by organizations is not yet wide spread.
Lourida, Katerina   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Is the network capable of computation? [PDF]

open access: yes2013 21st IEEE International Conference on Network Protocols (ICNP), 2013
Ensuring correct network behavior is hard. Previous state of the art has demonstrated that analyzing a network containing middleboxes is hard. In this paper, we show that even using only statically configured switches, and asking the simplest possible question – “Will this concrete packet reach the destination?” – can make the problem intractable ...
Peter Peresíni, Dejan Kostic
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

About the implantation process of mobile computing in AEC [PDF]

open access: yes, 2004
The AEC industry is conscious of the potentials arising from the usage of mobile computer systems to increase productivity by streamlining their business processes. Discussions are no longer on whether or not to use a mobile computer solution, but rather,
Dittrich, Jörg   +2 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

ConvTEBiLSTM: A Neural Network Fusing Local and Global Trajectory Features for Field-Road Mode Classification

open access: yesISPRS International Journal of Geo-Information
Field-road mode classification (FRMC) that identifies “in-field” and “on-road” categories for Global Navigation Satellite System (GNSS) trajectory points of agricultural machinery containing geographic information is essential for effective crop ...
Cunxiang Bian   +4 more
doaj   +1 more source

Security challenges of Small Cell as a Service in virtualized mobile edge computing environments [PDF]

open access: yes, 2016
Research on next-generation 5G wireless networks is currently attracting a lot of attention in both academia and industry. While 5G development and standardization activities are still at their early stage, it is widely acknowledged that 5G systems are ...
Haralambos Mouratidis   +6 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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