Results 71 to 80 of about 1,063,217 (316)

D3QN-Guided Sand Cat Swarm Optimization with Hybrid Exploration for Multi-Objective Cloud Task Scheduling

open access: yesAlgorithms
Task scheduling in cloud computing environments is a complex NP-hard problem that requires maximizing resource utilization while satisfying quality-of-service (QoS) constraints.
Minghao Shao   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A reputation-based dynamic reorganization scheme for blockchain network sharding

open access: yesConnection Science
While sharding technology helps solve performance bottlenecks in traditional blockchain networks, it also introduces new challenges. Random node allocation may lead to uneven distribution of malicious nodes, causing performance differences and security ...
Shuhui Zhang   +4 more
doaj   +1 more source

Academic Cloud computing research : five pitfalls and five opportunities

open access: yes, 2014
Date of Acceptance: 25/04/2014This discussion paper argues that there are five fundamental pitfalls, which can restrict academics from conducting cloud computing research at the infrastructure level, which is currently where the vast majority of academic
Jonathan Stuart Ward   +7 more
core  

State-of-the-Art in Parallel Computing with R [PDF]

open access: yes, 2009
R is a mature open-source programming language for statistical computing and graphics. Many areas of statistical research are experiencing rapid growth in the size of data sets. Methodological advances drive increased use of simulations.
Hao Yu   +11 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Category Attribute-Oriented Heterogeneous Resource Allocation and Task Offloading for SAGIN Edge Computing

open access: yesJournal of Sensor and Actuator Networks
Space-Air-Ground Integrated Network (SAGIN), which is considered a network architecture with great development potential, exhibits significant cross-domain collaboration characteristics at present.
Yuan Qiu   +4 more
doaj   +1 more source

Edge and Cloud Computing in Smart Cities

open access: yes
The evolution of smart cities is intrinsically linked to advancements in computing paradigms that support real-time data processing, intelligent decision-making, and efficient resource utilization.
Elias Dritsas, Maria Trigka
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A grid computing framework for commercial simulation packages

open access: yes, 2007
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An increased need for collaborative research among different organizations, together with continuing advances in communication technology and computer ...
Mustafee, Navonil
core  

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