Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Intelligent Wearable Rehabilitation System Based on Edge Computing. [PDF]
Chen CH, Wu YC, Chen JJ, Lin YC.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Architecture-Level Event-Oriented Frontend for Heterogeneous Sensor Inference in Photonic Stochastic Systems. [PDF]
Angelsky O +6 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Computational intelligence for simulating a LiDAR sensor
Castaño Romero, Fernando +3 more
openaire +2 more sources
Real-time cloud dataset of irradiance and temperature from edge-based monitoring. [PDF]
Restrepo-Cuestas B +4 more
europepmc +1 more source
Machine learning-assisted design of carbon nanotube edge computing circuits for monolithic epidermal systems. [PDF]
Luo Z +10 more
europepmc +1 more source
An Efficient Post-Quantum User Authentication Protocol for Wireless Sensor Networks Using NTRU. [PDF]
Shen W, Mo J, Lin Y.
europepmc +1 more source
A Context-Aware Adaptive Reasoning Framework for Dynamic Industrial Embodied Intelligence Systems. [PDF]
Jiang C, Liu H, Tian X.
europepmc +1 more source

