Results 221 to 230 of about 118,213,683 (284)

GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation

Advanced Science, EarlyView.
This study identifies the glucose/glutamine sensitive lncRNA GSLR as a driver of lung adenocarcinoma progression. Nutrient restriction reduces chromatin accessibility at the GSLR locus and blocks CTCF‐mediated transcriptional regulation. GSLR directly interacts with DHX9 and recruits it to the CKB promoter, arresting R‐loop accumulation and promoting ...
Xinyi Qian, Juze Yang, Jiayi Ren, Xiaowei Mao, Jia Li, Tengfei Sun, Liangliang Dong, Enguo Chen, Yan Lu, Pengyuan Liu   +9 more
wiley   +1 more source

Unintended Distal Embolisation of A Drug-Coated Balloon During Percutaneous Coronary Intervention: When Is Leaving the Device in Situ Feasible? [PDF]

Eur J Case Rep Intern Med
Alhazmi L.
europepmc   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

Advanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko, Dongyoon Shin, Junho Park, June Huh, Youngsoo Kim, Jong‐Wan Park   +5 more
wiley   +1 more source

Mechanism of coal mass fracture expansion under drilling and pressure relief. [PDF]

Sci Rep
Liu K, Liu Y, Lu CP, Zhou LH, Zhou QX, Wang C.   +5 more
europepmc   +1 more source

Horizontal In-Situ Stress Prediction of Shale Reservoirs in the W Well Area of Western Chongqing Based on Elastic Parameters from Prestack Seismic Inversion

Advances in Geoscience
Hong-Yu Liu
semanticscholar   +1 more source

Reaction‐Driven Self‐Organization of Nanocrystals by Kinetic Control of Inhomogeneous Photopolymerization

Advanced Science, EarlyView.
Patterned light reorganizes initially uniform CsPbBr3 perovskite quantum dots into well‐defined structures during photopolymerization. Using a digital micromirror device, we show that this reaction‐driven self‐organization is governed by a competition between chemical‐potential‐driven migration and kinetic arrest caused by rapid solidification ...
Kazuto Uchida, Shiryu Kitajima, Koki Ito, Hideyuki Nakanishi   +3 more
wiley   +1 more source

Deformation characteristics of weakly cemented overburden in Western mining areas in China. [PDF]

Sci Rep
Zhang G, Zhang H, Li G, Chen J, Zhao L, Zhou G.   +5 more
europepmc   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Editorial: Exploring plant stress responses using non-invasive light techniques. [PDF]

Front Plant Sci
Nožková V.
europepmc   +1 more source

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

Advanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu, Xi‐xiu Xie, Lei Li, Chen Tian, Hao‐tian Wang, Xiao‐jie Wang, Xiao‐lin Yu, Gui‐feng Zhang, Rui‐tian Liu   +8 more
wiley   +1 more source