Results 31 to 40 of about 46,054 (219)

Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching [PDF]

open access: yes, 2012
Bindarit, a selective inhibitor of monocyte chemotactic proteins (MCPs) synthesis, reduces neointimal formation in animal models of vascular injury and recently has been shown to inhibit in-stent late loss in a placebo-controlled phase II clinical trial.
Angelo Guglielmotti   +12 more
core   +3 more sources

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

open access: yesAdvanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang   +12 more
wiley   +1 more source

Current Treatment of In-Stent Restenosis

open access: yesJournal of the American College of Cardiology, 2014
Management of patients with in-stent restenosis (ISR) remains an important clinical problem. Although drug-eluting stents (DES) have drastically reduced the incidence of ISR, treatment of DES-ISR is particularly challenging. ISR mainly results from aggressive neointimal proliferation, but recent data also suggest that neoatherosclerosis may play an ...
Fernando Alfonso   +3 more
openaire   +3 more sources

Advances in procedural techniques--antegrade. [PDF]

open access: yes, 2014
There have been many technological advances in antegrade CTO PCI, but perhaps most importantly has been the evolution of the "hybrid' approach where ideally there exists a seamless interplay of antegrade wiring, antegrade dissection re-entry and ...
Spratt, JC, Wilson, W
core   +1 more source

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

open access: yesAdvanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang   +13 more
wiley   +1 more source

Inflammation and Restenosis in the Stent Era [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2002
The pathophysiology of restenosis involves early elements of direct injury to smooth muscle cells, deendothelialization, and thrombus deposition. Over time, this leads to smooth muscle cell proliferation/migration and extracellular matrix deposition. There is an increasing body of evidence to suggest that inflammation plays a pivotal role linking early
Campbell Rogers, Frederick G.P. Welt
openaire   +2 more sources

Biodegradable Medical Implants: Reshaping Future Medical Practice

open access: yesAdvanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia   +4 more
wiley   +1 more source

Stent Strut Thickness and Restenosis [PDF]

open access: yesCirculation, 2002
To the Editor: Kastrati et al recently reported1 significantly less restenosis with lesions randomized to deployment of one stent design (ACS RX Multi-Link, [ML]) than with a related design (Multi-Link RX Duet, [DT]) from the same manufacturer (Guidant). They attributed the difference in restenosis to the difference in strut thickness.
Peter Ruygrok   +2 more
openaire   +3 more sources

The Hybrid Approach to Intervention of Chronic Total Occlusions [PDF]

open access: yes, 2015
The "hybrid" approach to chronic total occlusion (CTO) percutaneous coronary intervention (PCI) was developed to provide guidance on optimal crossing strategy selection.
Banerjee, S   +6 more
core   +1 more source

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