Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su+6 more
wiley +1 more source
A new approach to planning in vitro and in vivo experiments for cardiovascular stents. (2) Planning of experiments [PDF]
Copyright @ 2000 Pacini Editore SpAWithin our overall project to improve the design of stents in terms of reduced rates of re-stenosis, there are three main methods, namely computer simulation and in vitro and in vivo experiments.
Atherton, MA+3 more
core
Introduction. Carotid endarterectomy versus carotid stenting. A never-ending story [PDF]
L'articolo discute le controversie relative all'accettazione in pratica clinica dello stentig ...
de Donato, Gianmarco+2 more
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ABSTRACT Background/Purpose We evaluated the outcomes of a new reconstruction method that we adopted in 2017 for small children with biliary atresia, involving aggressive resection of the sclerotic portal vein (PV), larger anastomotic orifice, and proactive vein graft interposition.
Hikaru Aoki+9 more
wiley +1 more source
Management of Subglottic Stenosis With the “Maddern Procedure”: Long Term Follow‐Up Outcomes
The Maddern procedure is an effective and durable option for patients with idiopathic subglottic stenosis. Five‐year recurrence‐free rate is 83%, and the mMRC dyspnea scale improves from 2.7 (SD 0.73) to 0.52 (SD 0.85). ABSTRACT Objective Full‐thickness resection and skin grafting of the laryngotracheal junction, the “Maddern Procedure,” can be used to
Emilie A. C. Dronkers+5 more
wiley +1 more source
Pharmacologic approaches against advanced glycation end products (ages) in diabetic cardiovascular disease [PDF]
Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients.
Avtaar Singh, Sanjeet Singh+6 more
core +2 more sources
Mucosal Grafts and Flaps in Draf IIb and Draf III: A Systematic Review and Meta‐analysis
Abstract Objective To evaluate the impact of mucosal grafts and flaps on neo‐ostium patency and clinical outcomes in patients undergoing Draf IIb or III frontal sinus drill‐out procedures. Data Sources A systematic search was conducted across PubMed, Medline, Cochrane Library, Scopus, and Web of Science databases in accordance with Preferred Reporting ...
Alexander Lein+8 more
wiley +1 more source
In-Stent Restenosis in the Drug-Eluting Stent Era
The introduction of the drug-eluting stent (DES) proved to be an important step forward in reducing rates of restenosis and target lesion revascularization after percutaneous coronary intervention. However, the rapid implementation of DES in standard practice and expansion of the indications for percutaneous coronary intervention to high-risk patients ...
George Dangas+5 more
openaire +3 more sources
Treatment of atherosclerotic renovascular hypertension: review of observational studies and a meta-analysis of randomized clinical trials. [PDF]
open9Atherosclerotic renal artery stenosis can cause ischaemic nephropathy and arterial hypertension. We herein review the observational and randomized clinical trials (RCTs) comparing medical and endovascular treatment for control of hypertension and ...
Caielli, P+8 more
core +1 more source
Impact of Immunosuppressive Drugs on Patients With Percutaneous Left Atrial Appendage Occlusion
ABSTRACT Introduction Percutaneous left atrial appendage closure (LAAC) reduces the risk of thromboembolic stroke in patients with non‐valvular atrial fibrillation who cannot tolerate long‐term oral anticoagulation. However, outcomes after LAAC in patients requiring chronic immunosuppressive therapy (IMS) remain unknown. This study aimed to investigate
Daisuke Togashi+7 more
wiley +1 more source