Results 221 to 230 of about 114,871,075 (252)

Navigating complexity: Evaluating management measures for multispecies snapper-grouper fisheries in the Southeast U.S. Atlantic. [PDF]

PLoS One
Cao J, Shertzer K, Crosson S, Williams E, DeVictor R.   +4 more
europepmc   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Clinical utility of renal and urinary tract point-of-care ultrasound in the neonatal intensive care unit: insights from a case series. [PDF]

Front Pediatr
Morajkar G, Deshpande S, Verma S, Goyal V, Hazarika J, Bansal P, Singh Y, Suryawanshi P.   +7 more
europepmc   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Investigation of Contrast Retention in PCOM Aneurysms as a Possible Marker for Instability and Rupture. [PDF]

Int J Numer Method Biomed Eng
Marsh LMM, Mut F, Chitsaz A, Lohner R, Robertson AM, Kaneko N, Cebral JR.   +6 more
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Core Acupoints and Acupoint Combination Patterns for Acupuncture Treatment of Discogenic Low Back Pain: A Data Mining Study. [PDF]

J Pain Res
Dong Y, Xu Y, Wu S, Lai Q, Wang F, Zha W, Zhan Q.   +6 more
europepmc   +1 more source

High‐Density E. Coli Cultivation Arrays for Combinatorial Drug Testing With Subsequent Lipid Profiling by MALDI‐MS

Advanced Science, EarlyView.
High‐throughput antibiotic cross‐gradient assays on microdroplet arrays. A multichannel printhead together with five pressure regulators forms droplet arrays of up to 20 832 droplets within 25 minutes. Each droplet contains unique concentrations of antibiotics, allowing to moniture a vast spectrum of bacterial repsonses over night. The bacterial growth
M. Breitfeld, C. L. Dietsche, F‐L. Born, I. Onipko, L. Blaase, P. S. Dittrich   +5 more
wiley   +1 more source

Arterial Perivascular Space-Mediated Solute Transport in the Mouse Brain. [PDF]

Exploration (Beijing)
Li S, Wang Y, Jia G, Yu Y, Zhang Z, Wang Q, Becker KV, Engle JW, Jiang D, Cai W.   +9 more
europepmc   +1 more source

Targeted cell deposition for lung re-endothelialization. [PDF]

Biomech Model Mechanobiol
Chan JKD, Chadwick EA, Taniguchi D, Ahmadipour M, Suzuki T, Romero D, Amon C, Waddell TK, Karoubi G, Bazylak A.   +9 more
europepmc   +1 more source