Results 21 to 30 of about 118,893,353 (307)

In Vitro Models to Study Hepatotoxicity [PDF]

open access: yesToxicologic Pathology, 2002
Drug discovery and development consists of a series of processes starting with the demonstration of pharmacologica l effects in experimental cell and animal models and ending with drug safety and effi cacy studies in patients. A main limitation is often the unacceptabl e level of toxicity with the liver as the primary target organ.
David A, Groneberg   +2 more
openaire   +2 more sources

Establishment of contaminant-free perennial plants in vitro

open access: yes, 1999
Perennial plant tissue cultures are established by disinfecting field or greenhouse-grown plant parts and transferring them to sterile medium in vitro. Typically, shoots harvested from field or greenhouse-grown plants are placed in water, either to force
McMeans O.M.   +5 more
core   +1 more source

Role of metformin in male oxidative stress infertility (MOSI):

open access: yesPakistan Journal of Pharmaceutical Sciences
The study aimed to determine the in-vitro effect of metformin on total antioxidant capacity (TAC) of seminal samples of infertile male subjects. It was conducted from January to June 2022 on forty-four seminal plasma samples collected from male infertile
An in vitro experimental study Nida Farooqui   +5 more
doaj   +1 more source

Drilling Capability of Orthodontic Miniscrews: In Vitro Study

open access: yesDentistry Journal, 2020
The aims of this study were to assess the values and mechanical properties of insertion torque (IT) of steel miniscrews inserted in artificial bone blocks (Sawbones, Pacific Research Laboratories, Vashon, WA, USA) with different bone densities and to ...
Alessandra Marchi   +5 more
doaj   +1 more source

Effects of collagen gel configuration on behaviour of vascular smooth muscle cells in vitro: association with vascular morphogenesis.

open access: yes, 2000
The growth, behavior, and contractile protein expression of rabbit aortic smooth muscle cells (SMC) grown on, between layers, or within a collagen gel was investigated by confocal laser scanning fluorescence microscopy and Western analysis.
Campbell, JH   +9 more
core   +1 more source

The effect of airborne Palladium nanoparticles on human lung cells, endothelium and blood-A combinatory approach using three in vitro models

open access: yes, 2023
A better understanding of the mechanisms behind adverse health effects caused by airborne fine particles and nanoparticles (NP) is essential to improve risk assessment and identification the most critical particle exposures.
Ulrika Johansson   +17 more
core   +1 more source

In Vitro Studies on Odontogenic Tumors [PDF]

open access: yes, 2012
Ameloblastomas are uncommon benign neoplasms of the jaws. They originate from dental epithelial cells, but they are not capable of mineralizing or forming enamel. The study of these tumors is limited to live tissue collected from patients during scheduled surgery.
Catón, Javier   +2 more
openaire   +3 more sources

Cholinesterase Reactivation: In Vitro Studies [PDF]

open access: yesAnaesthesia and Intensive Care, 1975
In vitro studies confirm the clinical impression that P–2–AM does not reverse the cholinesterase inhibition caused by organophosphorus insecticides.
A, Ganendran, S, Balabaskaran
openaire   +2 more sources

Comparative In-vitro Analysis of Fracture Strength in 3D-printed VarseoSmile TriniQ Resin Versus Milled Monolithic Zirconia Endocrowns: Advancing Restorative Material Performance

open access: yesDubai Medical Journal
Introduction: Restoring endodontically treated teeth requires materials that balance mechanical strength and tooth preservation. Endocrowns provide a conservative approach compared to conventional post-and-core restorations. While monolithic zirconia is
Okba Mahmoud   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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