MYC upstream region orchestrates resistance to PI3K inhibitors in cancer cells through FOXO3a-mediated autophagic adaptation [PDF]
The MYC oncogene is frequently overexpressed in tumors and inhibition of its translation is considered an attractive therapeutic opportunity. Despite numerous reports proposing an internal ribosome entry site (IRES) within the MYC Upstream Region (MYC ...
Alessandro Fatica+16 more
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MATHICSE Technical Report: Simulation-Based Anomaly Detection and Damage Localization: an Application to Structural Health Monitoring [PDF]
We propose a simulation-based decision strategy for the proactive maintenance of complex structures with a particular application to structural health monitoring (SHM).
Bigoni, Caterina, Hesthaven, Jan S.
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The treatment of displaced distal radius fractures in older patients
Executive Summary Distal radius fractures represent a significant challenge to health systems given that they are common, that they can be costly to treat and that presentation rates are rising in older populations.
Lawson, Andrew
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Chapter 3- Mechanisms of Fish Sound Production [PDF]
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Fine, Michael, Parmentier, Eric
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Intertemporal similarity: Discounting as a last resort [PDF]
Standard models of intertemporal choice assume that individuals discount future payoffs by integrating reward amounts and time delays to generate a discounted value.
Stevens, Jeffrey R.
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Non-equilibrium statistical mechanics: From a paradigmatic model to biological transport
Unlike equilibrium statistical mechanics, with its well-established foundations, a similar widely-accepted framework for non-equilibrium statistical mechanics (NESM) remains elusive. Here, we review some of the many recent activities on NESM, focusing on
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Identification Of The Third/Extra Allele For Forensic Application In Cases With Tpox Tri-Allelic Pattern [PDF]
Clarice Sampaio Alho+5 more
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Radio Resource Management for eXtended Reality [PDF]
This thesis addresses the challenges of supporting extended reality (XR) applications in fifth-generation (5G)-Advanced. It proposes practical radio resource management solutions focusing on three key areas: First, it develops enhanced link adaptation ...
Paymard, Pouria
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The asbian to arnsbergian conodonts and sequence stratigraphy of the Northumberland trough [PDF]
Yoredale sequences are excellent exemplars of the sequence stratigraphy model; the spacial and temporal variation of these complex shallow marine/fluvio-deltaic/ coastal plain cycles, exhibit all the uiternal facies architecture that would be expected of
Bowden, Alistair
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BARYON CONTENT TO THE OUTSKIRTS OF LOW-TEMPERATURE POOR GALAXY GROUPS [PDF]
Little is known concerning the overall properties of galaxy groups, especially at large radii. A better understanding of them will constrain numerical simulations regarding their formation and evolution, as well as reveal what role they play in the ...
Nugent, Jenna
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