Results 251 to 260 of about 423,064 (316)

Generative and Experimental Validation of High Refractive Index Polymers via Domain Knowledge Approach with Small Data

Advanced Intelligent Discovery, EarlyView.
This research demonstrates that the combination of domain knowledge–based multiple regression, multi‐objective Bayesian optimization, and generative models is a suitable prediction tool for candidates of high refractive index polymers, even with the constraints in the model trained on limited data. The experimental validation can reproduce the proposed
Takuya Yokoo, Seigo Watanabe, Hana Matsunaga, Kenichi Oyaizu   +3 more
wiley   +1 more source

Functional Annotation and Molecular Characterization of a Hypothetical Protein From <i>Mycobacterium leprae</i> Through <i>In Silico</i> Approaches: A Potential Therapeutic Target. [PDF]

Evol Bioinform Online
Tanha TH, Saikat S, Hasan R, Yeamin MMH, Parvin R, Imtiaz M, Hasib M.   +6 more
europepmc   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source

In Silico Perturbation Identifies Transcription Factors as Protective Targets in HSPCs After Irradiation. [PDF]

Int J Mol Sci
Tao Z, Zhang Q, Chen Y, Lv S, Huang Q, Tian H, Liu Q, Li C, Wang Y, Lu H, Quan C, Chen H, Lu Y, Zhou G.   +13 more
europepmc   +1 more source

Microrobotic Catheterization of the Ophthalmic Artery for Targeted Treatment of Retinoblastoma

Advanced Intelligent Systems, EarlyView.
A microrobotic platform is presented that allows teleoperated and autonomous navigation of flow‐driven magnetic microcatheters, MagFlow, into the ophthalmic artery for superselective intra‐arterial infusion of chemotherapy to treat retinoblastoma. Extensive benchtop validations with patient‐derived biomimetic phantoms under optical and fluoroscopic ...
Artur Banach, Mehdi Krichen, Julian Raub, Christina Stathopoulos, Bruno Bartolini, Mahmut Selman Sakar   +5 more
wiley   +1 more source

MeDReaders 2.0: an updated database for modified DNA readers. [PDF]

BMC Genomics
Li H, Zhou M, Luo X, Wang G.
europepmc   +1 more source

A diffusion model conditioned on compound bioactivity profiles for generating high-content images. [PDF]

Sci Rep
Cook S, Chyba J, Gresoro L, Quackenbush D, Qiu M, Kutchukian P, Martin EJ, Skewes-Cox P, Godinez WJ.   +8 more
europepmc   +1 more source

From Algorithms to Assets: A Comprehensive Review of AI's Role in Preclinical Drug Discovery and the Hurdles to Clinical Translation. [PDF]

Pharmaceuticals (Basel)
Cai M, Liu T.
europepmc   +1 more source