Results 91 to 100 of about 261,136 (339)

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

open access: yesBiological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon   +5 more
wiley   +1 more source

Immune reconstitution inflammatory syndrome accompanied by transient immune and chromosomal abnormality after azathioprine exposure in utero

open access: yesImmunological Medicine
Azathioprine (AZA) is widely used during pregnancy to manage autoimmune diseases; however, concerns regarding fetal immunological vulnerability persist. Although neonatal lymphocytopenia and chromosomal abnormalities have been reported following prenatal
Ryoko Yokoyama, Yoji Uejima
doaj   +1 more source

Sex-dependent effects of in utero cannabinoid exposure on cortical function

open access: yeseLife, 2018
Cannabinoids can cross the placenta, thus may interfere with fetal endocannabinoid signaling during neurodevelopment, causing long-lasting deficits.
Anissa Bara   +11 more
doaj   +1 more source

Early‐Life Clinical Factors Shape Cerebellar Structure in Preterm‐Born Children

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective Preterm birth alters typical brain development due to complex exposures related to neonatal illness, pain management, and brain injury. Despite an increased understanding of neonatal brain injury on developmental outcomes, the association of cerebellar maturation with school‐age motor and cognitive function remains incompletely ...
Victoria Rapos   +6 more
wiley   +1 more source

Hydrops fetalis associé à la toxoplasmose maternelle: à propos d'une observation et revue de la littérature

open access: yesThe Pan African Medical Journal, 2018
Les auteurs rapportent un cas d'hydrops fetalis diagnostiqué et pris en charge aux Cliniques Universitaires de Lubumbashi en République Démocratique du Congo.
Michel Kasonga Kasonga   +6 more
doaj   +1 more source

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]

open access: yes, 2015
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...
Ab Hamid, Hasiah   +173 more
core   +11 more sources

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez   +4 more
wiley   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco   +8 more
wiley   +1 more source

Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age [PDF]

open access: yes, 2019
Fetal programming associated with intrauterine growth restriction (IUGR) leads to lifelong deficits in growth and metabolic function (Hales and Barker, 2013).
Beard, Joslyn K.   +7 more
core   +1 more source

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