Results 171 to 180 of about 517,738 (337)

[Retracted] Analysis of Causes and Results of Fetal Growth in Utero Caused by Genetic Factors Detected by Ultrasound [PDF]

, 2022
Mei Yu, Ying Liu, Liya Wang
openalex   +1 more source

Automatic Respiratory and Bulk Patient Motion Corrected 3D Fetal MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT PurposeTo develop a framework (ACROBATIC) for correcting motion in 3D radial fetal MRI. MethodsData were simulated (N = 200) and acquired in utero (N = 11, gestational age: 32 ± 2 weeks). Motion due to maternal respiration was estimated by extracting a self‐gating signal and applying focused navigation.
Robin Ferincz, Leonor Alamo, Aurelio Secinaro, Estelle Tenisch, Aurélien Bustin, Davide Piccini, Milan Prša, Jérôme Yerly, Christopher W. Roy   +8 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

<i>In utero</i> thirdhand smoke exposure modulates platelet function in a sex-dependent manner

, 2021
Hamdy Ali, Ahmed B. Alarabi, Zubair A. Karim, Victor Rodriguez, Keziah R. Hernandez, Patricia A. Lozano, Medhat S. El-Halawany, Fatima Z. Alshbool, Fadi T. Khasawneh   +8 more
openalex   +2 more sources

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

In Utero Drug Withdrawal [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Diagnostic Accuracy of Estimated Fetal Weight Discordance in Predicting Birthweight Discordance in Monochorionic Twins: A Retrospective Cohort Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the diagnostic accuracy of sonographic estimated fetal weight discordance (EFWD) ≥ 20% in predicting birthweight discordance (BWD) ≥ 20% (i.e., selective fetal growth restriction [sFGR]) in monochorionic (MC) twin pregnancies.
Jip A. Spekman, E. J. T. Joanne Verweij, Femke Slaghekke, Monique C. Haak, Chiara C. M. M. Lap, Derek P. de Winter, Jeanine M. M. van Klink, Enrico Lopriore, Sophie G. Groene   +8 more
wiley   +1 more source

In Utero Diagnosis of Niemann–Pick Type C in the Absence of Family History

, 2015
Estelle Colin, Magalie Barth, F. Boussion, Philippe Latour, Guénaelle Piguet-Lacroix, Agnès Guichet, Alban Ziegler, Stéphane Triau, D. Loisel, Loı̈c Sentilhes, Dominique Bonneau   +10 more
openalex   +1 more source

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source