Results 11 to 20 of about 517,738 (337)

A systematic review of in utero cannabis exposure and risk for structural birth defects

Frontiers in Pediatrics, 2023
IntroductionCannabis use among pregnant women has increased over time. Therefore, there is a great public health need to understand the consequences of in utero cannabis exposure. While several meta-analyses and reviews have summarized the evidence of in
Ayesha C. Sujan, Ayesha C. Sujan, Anish Pal, Anish Pal, Lyndsay A. Avalos, Kelly C. Young-Wolff, Kelly C. Young-Wolff   +6 more
doaj   +2 more sources

In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2019
Early life exposure to fine particulate matter (PM) in air is associated with infant respiratory disease and childhood asthma, but limited epidemiological data exist concerning the impacts of ultrafine particles (UFPs) on the etiology of childhood ...
Chang, Richard C-A, Golding, Michael C, Johnson, Natalie M, Langley, Rebecca, Lau, Carmen, Leal, Jeann, Li, Yixin, Molina, Mario J, Myatt, Louise G, Pulczinski, Jairus, Raju, Muppala, Rodrigues-Hoffmann, Aline, Rychlik, Kristal A, Secrest, Jeremiah R, Zamora, Misti L, Zhang, Renyi   +15 more
core   +2 more sources

Functional brain connectivity in ex utero premature infants compared to in utero fetuses

NeuroImage, 2020
Brain structural changes in premature infants appear before term age. Functional differences between premature infants and healthy fetuses during this period have yet to be explored. Here, we examined brain connectivity using resting state functional MRI
Josepheen De Asis-Cruz, Kushal Kapse, Sudeepta K. Basu, Mariam Said, Dustin Scheinost, Jonathan Murnick, Taeun Chang, Adre du Plessis, Catherine Limperopoulos   +8 more
doaj   +2 more sources

Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection.

JAMA pediatrics, 2022
Importance Associations between in utero exposure to maternal SARS-CoV-2 infection and neurodevelopment are speculated, but currently unknown. Objective To examine the associations between maternal SARS-CoV-2 infection during pregnancy, being born ...
Lauren C. Shuffrey, Morgan R. Firestein, Margaret H. Kyle, Andrea Fields, C. Alcántara, Dima Amso, J. Austin, J. Bain, Jennifer R. Barbosa, Mary Bence, Catherine Bianco, Cristina R. Fernández, Sylvie Goldman, C. Gyamfi‐Bannerman, Violet Hott, Yunzhe Hu, Maha Hussain, P. Factor-Litvak, M. Lucchini, Arthur M. Mandel, R. Marsh, D. McBrian, M. Mourad, R. Muhle, Kimberly G Noble, A. Penn, C. Rodriguez, A. Sania, Wendy G. Silver, Kally C. O'Reilly, M. Stockwell, Nim Tottenham, M. Welch, N. Zork, W. Fifer, C. Monk, D. Dumitriu   +36 more
semanticscholar   +1 more source

The impact of timing of in utero marijuana exposure on fetal growth

Frontiers in Pediatrics, 2023
Objective To examine whether timing of in utero marijuana exposure independently and negatively impacts fetal growth, and if these effects are global or specific to certain growth parameters.
P. Dodge, K. Nadolski, H. Kopkau, V. Zablocki, K. Forrestal, Beth Bailey   +5 more
semanticscholar   +1 more source

In Utero Enzyme-Replacement Therapy for Infantile-Onset Pompe's Disease.

New England Journal of Medicine, 2022
Patients with early-onset lysosomal storage diseases are ideal candidates for prenatal therapy because organ damage starts in utero. We report the safety and efficacy results of in utero enzyme-replacement therapy (ERT) in a fetus with CRIM (cross ...
Jennifer L. Cohen, P. Chakraborty, K. Fung-Kee-Fung, M. E. Schwab, D. Bali, S. Young, M. Gelb, Hamid Khaledi, A. DiBattista, S. Smallshaw, F. Moretti, Derek Wong, C. Lacroix, D. El Demellawy, Kyle C. Strickland, J. Lougheed, A. Moon‐Grady, B. Lianoglou, P. Harmatz, P. Kishnani, T. Mackenzie   +20 more
semanticscholar   +1 more source

Ionizable lipid nanoparticles for in utero mRNA delivery

Science Advances, 2021
Lipid nanoparticles deliver mRNA to mouse fetuses, which may ultimately enable in utero therapy to treat fetal genetic diseases. Clinical advances enable the prenatal diagnosis of genetic diseases that are candidates for gene and enzyme therapies such as
Rachel S. Riley, Meghana V. Kashyap, Margaret M. Billingsley, Brandon M. White, M. Alameh, S. Bose, P. Zoltick, Hiaying Li, R. Zhang, Andrew Y. Cheng, D. Weissman, W. Peranteau, M. J. Mitchell   +12 more
semanticscholar   +1 more source

Birth Outcomes of Neonates Exposed to Marijuana in Utero

JAMA Network Open, 2022
This systematic review and meta-analysis compares adverse neonatal outcomes among mothers exposed to marijuana during pregnancy vs mothers not exposed to marijuana during pregnancy in 16 cohort studies.
Greg J. Marchand, A. Masoud, M. Govindan, K. Ware, A. King, S. Ruther, G. Brazil, H. Ulibarri, J. Parise, A. Arroyo, C. Coriell, S. Goetz, Amitis Karrys, K. Sainz   +13 more
semanticscholar   +1 more source

Bovine Animal Model for Studying the Maternal Microbiome, in utero Microbial Colonization and Their Role in Offspring Development and Fetal Programming

Frontiers in Microbiology, 2022
Recent developments call for further research on the timing and mechanisms involved in the initial colonization of the fetal/infant gut by the maternal microbiome and its role in Developmental Origins of Health and Disease (DOHaD).
S. Amat, C. Dahlen, K. Swanson, A. Ward, L. Reynolds, J. Caton   +5 more
semanticscholar   +1 more source

Immune function in newborns with in-utero exposure to anti-TNFα therapy

Frontiers in Pediatrics, 2022
Background and aim Anti-TNFα is measurable in infants exposed in utero up to 12 months of age. Data about the exposure effect on the infant’s adaptive immunity are limited. We aimed to prospectively evaluate the distribution and function of T and B cells,
B. Weiss, S. Ben-Horin, A. Lev, E. Broide, M. Yavzori, A. Lahat, U. Kopylov, O. Picard, R. Eliakim, Y. Ron, I. Avni-Biron, A. Yerushalmy-Feler, A. Assa, R. Somech, A. Bar-Gil Shitrit   +14 more
semanticscholar   +1 more source