Results 81 to 90 of about 517,738 (337)
In utero nanoparticle delivery for site-specific genome editing
Nature Communications, 2018 Genetic diseases can be diagnosed early during pregnancy, but many monogenic disorders continue to cause considerable neonatal and pediatric morbidity and mortality. Early intervention through intrauterine gene editing, however, could correct the genetic
A. Ricciardi +16 more
semanticscholar +1 more source
Natural Selection _In Utero_ Contributes to the Male Longevity Deficit in Contemporary Human Populations [PDF]
, 2009 Much literature invokes natural selection to explain the pervasive deficit in the average lifespan of men compared to women.^1^ The explanation assumes that mothers, not fathers, provisioned children over much of human existence, and that women who lived
Ralph Catalano
core +1 more source
Training the Fetal Immune System Through Maternal Inflammation-A Layered Hygiene Hypothesis. [PDF]
, 2020 Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the immune
Apostol, April C +2 more
core
Distal femoral morphology as a risk factor for osteoarthritis
The Anatomical Record, EarlyView.Abstract Osteoarthritis (OA) is a leading cause of disability affecting millions of adults in the United States, commonly resulting in the need for total knee arthroplasty (TKA) to restore mobility and quality of life. This study investigates potential differences in baseline distal femoral shape between individuals who received TKA due to OA and a ...
Haley Horbaly
wiley +1 more source
Sex differences in fetal intracranial volumes assessed by in utero MR imaging
Biology of Sex Differences, 2023 Background The primary aim of the study is to test the null hypothesis that there are no statistically significant differences in intracranial volumes between male and female fetuses.
Paul D. Griffiths +3 more
doaj +1 more source
Neurodevelopmental delay in normocephalic children with in utero exposure to Zika virus
BMJ Paediatrics Open, 2019 Neurodevelopment in 29 normocephalic children with in utero exposure to Zika virus (ZIKV) was evaluated by the Bayley Scales of Infant and Toddler Development-Third Edition. Ten (35%) infants presented neurodevelopment delay.
A. Faiçal +7 more
semanticscholar +1 more source
Ontogeny of murine bony semicircular canal form
The Anatomical Record, EarlyView.Abstract The labyrinthine geometry and functional anatomy of the semicircular canals have intrigued scientists for decades, and there has been considerable interest in understanding how these complex structures grow and develop with evidence emerging from human studies that size maturation occurs exceptionally early by comparison with other systems ...
Marcela Cárdenas‐Serna +1 more
wiley +1 more source
Microbiome, 2021 A recent study by Rackaityte et al. reported evidence for a low level of bacterial colonization, specifically of Micrococcus luteus, in the intestine of second trimester human fetuses. We have re-analyzed their sequence data and identified a batch effect
Marcus C. de Goffau +3 more
doaj +1 more source
Maternal inflammation at 0.7 gestation in ewes leads to intrauterine growth restriction and impaired glucose metabolism in offspring at 30 d of age [PDF]
, 2019 Fetal programming associated with intrauterine growth restriction (IUGR) leads to lifelong deficits in growth and metabolic function (Hales and Barker, 2013).
Beard, Joslyn K. +7 more
core +1 more source
Neurodevelopment in Infants Exposed to Zika Virus In Utero.
New England Journal of Medicine, 2018 Zika Virus and Neurodevelopment Exposure to Zika virus in utero has been associated with neurodevelopmental abnormalities. In this letter, the results of long-term follow-up of Brazilian children exposed to ZIKV in utero are reported.
M. E. Lopes Moreira +34 more
semanticscholar +1 more source