Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran +15 more
wiley +1 more source
Machine Learning-Enabled Meta-Analysis of Bioengineering Micro- and Nanorobots. [PDF]
Rahimi E +5 more
europepmc +1 more source
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn +6 more
wiley +1 more source
Methane mitigation, nutritional evaluation, and in vitro degradation kinetics of diets based on tropical grass haylage treated with xylanase. [PDF]
Duarte ABA +12 more
europepmc +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
Upgrading the feeding value of oil palm fronds for ruminants through processing: Evidence from a meta-analysis of <i>in vitro</i> and <i>in vivo</i> studies. [PDF]
Rahmadani M +7 more
europepmc +1 more source
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
A Novel Feed Additive Derived from Mushroom-Based Phytonutrients: Effects on Rumen Antioxidant Capacity, Fermentation, and Methane Production. [PDF]
Matra M +4 more
europepmc +1 more source
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar +6 more
wiley +1 more source
Effects of Rosemary, Citronella, and Tea Tree Essential Oils on Fermentation Characteristics and Aerobic Stability of Sorghum Silage. [PDF]
Júnior JRM +7 more
europepmc +1 more source

