Results 51 to 60 of about 14,911 (263)
The in situ dry matter (DM) disappearance of corn silages in two maturity stages (milk grain and half milk line) of known in vivo and in vitro digestibility was determined, with the main purpose of comparing digestibility values with the ruminal ...
O.N. Di Marco, M.S. Aello, S. Arias
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Qinghui Zhao1 12 23 3,* Hongming Tang1 12 23 3,* Lishu Ren4 4, Jie Wei4 4 1School of Life Sciences and Technology, Tongji University, Shanghai 200092, People’s Republic of China; 2Translational Medical Center for Stem Cell Therapy & Institute ...
Zhao Q, Tang H, Ren L, Wei J
doaj
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Innovative procedures to evaluate corn silage for milk yield
Corn silage is the main ingredient of diets for dairy cattle (around 40% of diet DM in Italy) and, therefore, an accurate estimation of its nutritive value is essential to describe the whole diet.
C. Zanfi, M. Spanghero
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Maize stover has potential as ruminant feed because it has good nutritional value and is abundant. Its perishable nature makes maize stover cannot stand for a long time. It is important to conserve maize stover especially in from of silage and utilize it
Arsianty Y.N. +4 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The in situ degradation of the washout fraction of starch in six feed ingredients (i.e. barley, faba beans, maize, oats, peas and wheat) was studied by using a modified in situ protocol and in vitro measurements.
L.H. de Jonge, H. van Laar, J. Dijkstra
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