Results 51 to 60 of about 14,911 (263)

Digestibility and ruminal digestion kinetics of corn silage Digestibilidade e cinética da digestão no rúmen de silagem de milho

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
The in situ dry matter (DM) disappearance of corn silages in two maturity stages (milk grain and half milk line) of known in vivo and in vitro digestibility was determined, with the main purpose of comparing digestibility values with the ruminal ...
O.N. Di Marco, M.S. Aello, S. Arias
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

In vitro Apatite Mineralization, Degradability, Cytocompatibility and in vivo New Bone Formation and Vascularization of Bioactive Scaffold of Polybutylene Succinate/Magnesium Phosphate/Wheat Protein Ternary Composite

open access: yesInternational Journal of Nanomedicine, 2020
Qinghui Zhao1 12 23 3,* Hongming Tang1 12 23 3,* Lishu Ren4 4, Jie Wei4 4 1School of Life Sciences and Technology, Tongji University, Shanghai 200092, People’s Republic of China; 2Translational Medical Center for Stem Cell Therapy & Institute ...
Zhao Q, Tang H, Ren L, Wei J
doaj  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Innovative procedures to evaluate corn silage for milk yield

open access: yesItalian Journal of Animal Science, 2010
Corn silage is the main ingredient of diets for dairy cattle (around 40% of diet DM in Italy) and, therefore, an accurate estimation of its nutritive value is essential to describe the whole diet.
C. Zanfi, M. Spanghero
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

EVALUATION OF MAIZE STOVER SILAGE QUALITY PREPARED WITH DIFFERENT LEVEL OF PEDIOCOCCUS ACIDILACTICI BACTERIA AS INOCULANT

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2021
Maize stover has potential as ruminant feed because it has good nutritional value and is abundant. Its perishable nature makes maize stover cannot stand for a long time. It is important to conserve maize stover especially in from of silage and utilize it
Arsianty Y.N.   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Estimation of the in situ degradation of the washout fraction of starch by using a modified in situ protocol and in vitro measurements

open access: yesAnimal, 2015
The in situ degradation of the washout fraction of starch in six feed ingredients (i.e. barley, faba beans, maize, oats, peas and wheat) was studied by using a modified in situ protocol and in vitro measurements.
L.H. de Jonge, H. van Laar, J. Dijkstra
doaj   +1 more source

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