Results 81 to 90 of about 39,460 (303)

CCDC41 Drives Oocyte Meiotic Progression by Promoting Rab11a/Rab7‐Positive Vesicle Fusion with Target Membranes

Advanced Science, EarlyView.
CCDC41 is essential for meiotic maturation in mouse oocytes through regulating Rab7‐positive endosomes fusion with lysosomes and Rab11a‐positive vesicle fusion with the plasma membrane. Abstract Coiled‐coil domain‐containing protein 41 (CCDC41), a core component of centriolar distal appendages involved in centriole assembly and ciliary vesicle docking,
Ying Tian, Jiatong Li, Jingyi Kang, Xiangning Xu, Bicheng Wang, Shuo Lou, Jingyu Li, Yuying Yang, Yanbing Zhang, Yangzi Zheng, Jing Weng, Yuanjing Liang, Wei Ma   +12 more
wiley   +1 more source

Should We Be Offering Intracytoplasmic Sperm Injection to All Couples with Unexplained Infertility: A Cohort Study

Journal of Human Reproductive Sciences
Background: In unexplained infertility (UI), the use of intracytoplasmic sperm injection (ICSI) has been increased to prevent total fertilisation failure (TFF). However, there is little evidence to support improved clinical outcomes.
Neeta Singh, Neena Malhotra, Reeta Mahey, Supriya Kumari, Monika Saini, Nisha   +5 more
doaj   +1 more source

Lentiviral vector transduction of spermatozoa as a tool for the study of early development

FEBS Open Bio, 2014
Spermatozoa and lentiviruses are two of nature’s most efficient gene delivery vehicles. Both can be genetically modified and used independently for the generation of transgenic animals or gene transfer/therapy of inherited disorders.
Anil Chandrashekran, Ihsan Isa, Jayesh Dudhia, Adrian J. Thrasher, Nicholas Dibb, Colin Casimir, Carol Readhead, Robert Winston   +7 more
doaj   +1 more source

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Gene expression analysis of bovine embryonic disc, trophoblast and parietal hypoblast at the start of gastrulation [PDF]

, 2017
In cattle early gastrulation-stage embryos (Stage 5), four tissues can be discerned: (i) the top layer of the embryonic disc consisting of embryonic ectoderm (EmE); (ii) the bottom layer of the disc consisting of mesoderm, endoderm and visceral hypoblast
Berg, D, Maclean, P, Pfeffer, P, Smith, C   +3 more
core   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Clinical Use of Non-Invasive Preimplantation Genetic Testing – A Joint Position Statement from the Indian Society for Assisted Reproduction, Indian Fertility Society and Academy of Clinical Embryologists

Journal of Human Reproductive Sciences
The Indian Society for Assisted Reproduction (ISAR), Indian Fertility Society (IFS) and Academy of Clinical Embryologists (ACE) jointly recommend that non-invasive preimplantation genetic testing (niPGT) (whether using spent culture media or blastocoel ...
Deepak Modi, Gaurav Majumdar, Sayali Kandari, Varsha Samson Roy, Parasuram Gopinath, Asha Baxi, Vanshika Jain, Sujatha Ramakrishnan, Pankaj Talwar, Ameet Patki   +9 more
doaj   +1 more source

OP18.04: Utilising machine learning algorithms to predict in vitro fertilisation cycle outcomes with endometrium as a key predictor [PDF]

, 2023
Y. Wang
openalex   +1 more source

The impact of female obesity on the outcome of fertility treatment [PDF]

, 2010
Peer reviewedPublisher ...
Abha Maheshwari, Ayyad, Balen, Balen, Bellver, Bellver, Bellver, Bergh, Brannian, Clark, Diamanti-Kandarakis, Dodson, Ehrmann, Gil-Campos, Hamilton-Fairley, Hollmann, Hossain, Huber-Buchholz, Imani, Imani, Jungheim, Kiddy, Koloszar, Law, Li, Maheshwari, Metwally, Metwally, Metwally, Moran, Moschos, Mulders, Nohr, Ogden, Orvieto, Palomba, Panidis, Pasquali, Prentice, Rich-Edwards, Shilpi Pandey, Siladitya Bhattacharya, Suruchi Pandey, Tang, The, Tsagareli, Van, Wadden, Wang, Wattanakumtornkul, Wise, Zaadstra, Zachariah, Zhang   +53 more
core   +3 more sources

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source