Results 201 to 210 of about 28,412 (311)
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
Development of an Efficient In Vitro Propagation Method for <i>Acmella oleracea</i> (L.) R.K. Jansen. [PDF]
Szarvas P +3 more
europepmc +1 more source
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan +11 more
wiley +1 more source
Integrated media and plant growth regulators comparative evaluation for enhanced in vitro propagation and acclimatization of Selenicereus Costaricensis. [PDF]
Ahmed EZ +5 more
europepmc +1 more source
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Recent advances in the use of plant growth promoting microorganisms for enhancing micropropagation efficiency. [PDF]
Guru GR +3 more
europepmc +1 more source
A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang +8 more
wiley +1 more source
Micropropagation and ex vitro acclimatization of Lonicera caerulea var. altaica: molecular identification and protocol optimization. [PDF]
Zhanybekova Z +4 more
europepmc +1 more source
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang +18 more
wiley +1 more source

